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- Title
UbcH10 overexpression is less pronounced in older colorectal cancer patients.
- Authors
Pellino, Gianluca; Pallante, Pierlorenzo; Malapelle, Umberto; Ferraro, Angelo; Bellevicine, Claudio; Milone, Marco; Troncone, Giancarlo; Fusco, Alfredo; Selvaggi, Francesco
- Abstract
The article presents a study which has found that UbcH10 protein overexpression is less pronounced in older colorectal cancer patients. Topics include UbcH10 protein found to be affecting tumor growth and sensitivity to treatments, and since the silencing of UbcH10 leads to a better response to treatment (synergistic effect), young patients found to benefit from evaluation of UbcH10.
- Subjects
PROTEIN expression; COLON cancer patients; OLDER patients; TUMOR growth; COLON cancer treatment
- Publication
International Journal of Colorectal Disease, 2016, Vol 31, Issue 7, p1367
- ISSN
0179-1958
- Publication type
Letter
- DOI
10.1007/s00384-015-2481-6