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- Title
An equation to predict peak heart rate for prescribing exercise intensity in middle-aged to older patients requiring hemodialysis.
- Authors
Oyanagi, Haruna; Usui, Naoto; Tsubaki, Atsuhiro; Ando, Shuji; Saithoh, Masakazu; Kojima, Sho; Inatsu, Akihito; Hisadome, Hideki; Ota, Shigeyuki; Uehata, Akimi
- Abstract
<bold>Purpose: </bold>Exercise prescription based on a population-specific physiological response can help ensure safe and effective physical interventions. However, as a facile approach for exercise prescription in hemodialysis population that is based on their exercise capacity has not yet been established, the aim of our study was to develop a unique prediction formula for peak heart rate (HR) that can be used in this population.<bold>Methods: </bold>This cross-sectional study measured physical function and HR at peak exercise and anaerobic threshold (AT) during cardiopulmonary exercise tests in 126 individuals. Participants were randomly assigned to the development group (n = 78), whose data were used to calculate the prediction equation, or the validation group (n = 48).<bold>Results: </bold>The HR reserve in this population was significantly lower (0.44 ± 0.20%) and there was a large discrepancy between conventional age-predicted maximal HR and measured peak-HR values (R = 0.36). The average of the ratio between HR at AT point and peak HR was 85% (95% CI, 83.5%-86.4%). The peak-HR prediction equation was based on resting HR, presence of diabetes, physical dysfunction (gait speed < 1.0 m/s), and hypoalbuminemia (< 3.5 g/dL). It showed high prediction accuracy (R2 [95%CI] = 0.71 [0.70-0.71]) with similar correlation coefficients between the development and validation groups (R = 0.82).<bold>Conclusion: </bold>Aerobic exercise based on estimated peak HR < 85% obtained from the equation in this study may enable safe and effective physical intervention in this population.
- Subjects
EXERCISE tests; RESEARCH; OXYGEN consumption; CROSS-sectional method; RESEARCH methodology; EVALUATION research; COMPARATIVE studies; RANDOMIZED controlled trials; HEART beat; HEMODIALYSIS
- Publication
European Journal of Applied Physiology, 2022, Vol 122, Issue 10, p2233
- ISSN
1439-6319
- Publication type
Article
- DOI
10.1007/s00421-022-05002-5