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- Title
A Surface Plasmon Resonance-Based Method for Detection and Determination of Cannabinoids Using Silver Nanoparticles.
- Authors
Amjadi, M.; Sodouri, T.
- Abstract
In this work, a simple colorimetric method based on the formation of silver nanoparticles (Ag NPs) was developed for the determination of cannabinoids including Δ-tetrahydrocannabinol (Δ-THC), cannabidiol (CBD) and cannabinol (CBN). These compounds in a basic solution at 80°C reduce [Ag(NH)] to form Ag NPs. The produced NPs were characterized by transmission electron microscopy and UV-Vis absorption spectroscopy. The brown-yellow color of the solution that results from the localized surface plasmon resonance of Ag NPs can be observed by the bare eye. The calibration graph obtained by plotting the absorbance at 410 nm versus the concentration of each analyte was linear in the range of 0.1-5.0 μg/ml for all tested cannabinoids. The limits of detection were 0.065, 0.077, and 0.052 μg/ml for Δ-THC, CBN and CBD, respectively. The developed method was applied to the determination of total cannabinoids in hashish.
- Subjects
SURFACE plasmon resonance; CANNABINOIDS; SILVER nanoparticles; TRANSMISSION electron microscopy; ABSORPTION spectra; CALIBRATION; HASHISH
- Publication
Journal of Applied Spectroscopy, 2014, Vol 81, Issue 2, p232
- ISSN
0021-9037
- Publication type
Article
- DOI
10.1007/s10812-014-9915-8