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- Title
SYNTHESIS OF SOME HETEROCYCLIC COMPOUNDS DERIVATIVES BY USING MELDRUM'S ACID AS STARTING MATERIAL AND STUDY OF THE BIOLOGICAL ACTIVITIES.
- Authors
Ali, Naji Mousa; Ameer Ghafil, Rajaa Abdul; Ghanim, Hassan T.
- Abstract
This paper involves synthesized of some heterocyclic compounds derivatives by using Meldrum's Acid as starting material by Multicomponent reaction of Meldrum's Acid, salisaldehyde and indol, Meldrum acid derivative, which further to synthesis Schiff base derivative after that Schiff base using to prepare of four, five, seven membered ring by reacted with different materials. Their structures were identified by (FT-IR, ¹HNMR, ¹CNMR). The synthetic compounds were screened in vitro antimicrobial for biological activity.
- Subjects
HETEROCYCLIC compounds synthesis; MALONIC acid; BETA lactamase kinetics; IMIDAZOLIDINES; IMINE derivatives; THERAPEUTICS
- Publication
Biochemical & Cellular Archives, 2018, Vol 18, Issue 1, p789
- ISSN
0972-5075
- Publication type
Article