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- Title
Exploration of hemolytic model of axial blood pump.
- Authors
Yanjiao Xuan; Yu Chang; Miao Song
- Abstract
Axial flow blood pumps provide additional energy to blood for heart failure patients, but its implanting destroys the environment of blood cells; the direct consequence is hemolysis. According to energy conservation theorem, the severity of pump hemolysis depends on the energy utilization ratio of it. This is a new train of thought in this field. In the light of it, it is necessary to clear up how much energy is used to pump blood, and so a portion of the remaining energy is the energy leading to hemolysis. At present, a complete hemolysis model of axial blood pump remains unknown. Based on the analysis of factors leading to hemolysis, this paper calculates the driving energy of blood pump from the angle of energy conservation, deduces the power for hemolysis, and then establishes a universally applicable hemolytic model of axial blood pump in normal operation conditions. Results: The relevant coefficients of it are derived from the in vivo experimental data. The setting up of mathematic model plays very important role in forecasting the hemolysis and improve the blood compatibility. This paper proposes a novel idea for hemolysis predicting of axial blood pump, which provides vital guidance for the design and improving of pumps control system and establishes a basis for follow-up work.
- Subjects
BLOOD flow; HEART failure; BLOOD cells; HEMOLYSIS &; hemolysins; ENERGY conservation
- Publication
Journal of Experimental & Integrative Medicine, 2012, Vol 2, Issue 4, p365
- ISSN
1309-4572
- Publication type
Article
- DOI
10.5455/jeim.300812.hp.005