We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Enaminonitrile as Building Block in Heterocyclic Synthesis: Synthesis of Novel 4H-Furo[2,3-d][1,3]oxazin-4-one and Furo[2,3-d]pyrimidin-4(3H)-one Derivatives.
- Authors
El-Shahawi, Manal M.; El-Ziaty, Ahmed K.
- Abstract
2-Amino-4,5-diphenylfuran-3-carbonitrile 1 was utilized as building block for the construction of new furo[2,3-d]pyrimidin-4(3H)-one derivative 2 and 4H-furo[2,3-d][1,3]oxazin-4-one derivative 3 via treatment with acetic anhydride and benzoyl chloride, respectively. The 4H-furo[2,3-d][1,3]oxazin-4-one derivative 3 was transformed into novel furo[2,3-d]pyrimidin-4(3H)-ones 4–8, tetrazolylfuran derivative 10, and furo[3,2-d]imadazolone derivative 11 via reaction with various nitrogen nucleophiles. The structure features of the synthesized compounds were established from their spectral and elemental analyses.
- Subjects
NITRILE derivatives; HETEROCYCLIC compounds synthesis; PYRIMIDINE derivatives; CHEMICAL structure; NUCLEOPHILES
- Publication
Journal of Chemistry, 2017, p1
- ISSN
2090-9063
- Publication type
Article
- DOI
10.1155/2017/5610707