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- Title
Four New Acyclic Diterpenes From Siegesbeckia orientalis.
- Authors
Do Thi Trang; Phan Thi Thanh Huong; Nguyen Thi Cuc; Duong Thi Dung; Bui Thi Thu Trang; Nguyen Xuan Nhiem; Bui Huu Tai; Phan Van Kiem
- Abstract
Four new acyclic diterpenes, siegetalises A-D (1-4), were isolated from the aerial parts of Siegesbeckia orientalis. Their chemical structures were elucidated by extensive analysis of high-resolution electrospray ionization mass spectrometry and nuclear magnetic resonance spectral data. The effects of the isolated compounds on the activity of xanthine oxidase were evaluated by the oxidative reaction with xanthine as a substrate. At a concentration of 50 µM, compounds 1-4 exhibited xanthine oxidase inhibitory activity at levels of 13.59% ±0.51%, 19.64% ±1.54%, 17.45% ±1.26%, and 21.36% ±1.40%, respectively.
- Subjects
DITERPENES; ELECTROSPRAY ionization mass spectrometry; XANTHINE oxidase; NUCLEAR magnetic resonance
- Publication
Natural Product Communications, 2021, Vol 16, Issue 11, p1
- ISSN
1934-578X
- Publication type
Article
- DOI
10.1177/1934578X211056140