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- Title
Retraction: Antidepressant-Like Activity of YL-0919: A Novel Combined Selective Serotonin Reuptake Inhibitor and 5-HT<sub>1A</sub> Receptor Agonist.
- Authors
Chen, Hong-xia; Jin, Zeng-liang; Zhang, Li-ming; Xue, Rui; Xu, Xiao-dan; Zhao, Nan; Qiu, Zhi-kun; Wang, Xian-wang; Zhang, You-zhi; Yang, Ri-fang; Li, Yun-feng
- Abstract
The article titled "Retraction: Antidepressant-Like Activity of YL-0919: A Novel Combined Selective Serotonin Reuptake Inhibitor and 5-HT1A Receptor Agonist" has been retracted by the corresponding author due to lack of confidence in the results. The authors discovered methodological errors in Tables 3 and 4, which rendered the results unreliable. It was found that YL-0919 is not a selective SERT/5-HT1A receptor agonist as previously reported. The experimental conditions used in the study led to significant degradation of the collected membrane protein, and the buffer used affected the binding results. The authors and the publisher apologize for the oversight.
- Subjects
SEROTONIN uptake inhibitors
- Publication
PLoS ONE, 2024, Vol 19, Issue 5, p1
- ISSN
1932-6203
- Publication type
Correction Notice
- DOI
10.1371/journal.pone.0304643