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- Title
Wildlife as a Source of SARS-CoV-2 Evolution-A Review.
- Authors
Altaf, Muhammad; Abbasi, Arshad Mahmood; Amjad, Muhammad Shoaib; Naseer, Sadia; Umair, Muhammad
- Abstract
Coronavirus consists of single-stranded, enveloped and RNA virus, largest genome among all RNA viruses and has 4 proteins i.e. envelope, spike, nucleocapsid and membrane. Coronaviruses are classified into 4 genera: Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Betacoronavirus most probably originated from bats and the virus may have jumped to avian species and evolved as Deltacoronavirus group. The avian coronaviruses jumped among other avian species, giving rise to Gammacoronavirus from Deltacoronavirus, while Betacoronavirus may have given rise to Alphacoronavirus. It is known that SARS-CoV-2 belongs to Betacoronavirus. This most similar virus is verified in bat and Malayan Pangolin. Analysis showed that SARS-CoV-2 most probably originated by recombination of both bat and pangolin viruses. Viral protein seroconversion and viral specific nucleotide positive documented in all COVID-19 patients tested provides confirmation of a link between the presence of this virus and the disease.
- Subjects
VIRUS diseases; SARS-CoV-2; CORONAVIRUSES; RNA viruses; BETACORONAVIRUS; BATS; COVID-19
- Publication
Pakistan Journal of Zoology, 2022, Vol 54, Issue 4, p1899
- ISSN
0030-9923
- Publication type
Article
- DOI
10.17582/journal.pjz/20200510100555