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- Title
In vivo label-free microangiography by laser speckle imaging with intensity fluctuation modulation.
- Authors
Mingyi Wang; Yaguang Zeng; Xianjun Liang; Guanping Feng; Xuanlong Lu; Junbo Chen; Dingan Han; Guojian Yang
- Abstract
We present the theory of laser speckle imaging improved with intensity fluctuation modulation, where the dynamic speckle pattern can be isolated from its stationary counterpart. A series of in vivo experiments demonstrate the effectiveness of our method in achieving microangiography and monitoring vascular self-recovering process. All results show the convincing performance of our imaging method in both structural and functional imaging of blood flow, which may have potential applications in biological research and disease diagnosis.
- Subjects
SPECKLE interference; FUNCTIONAL imaging sensors; BLOOD flow; DIAGNOSIS; RESEARCH; ATHEROSCLEROSIS
- Publication
Journal of Biomedical Optics, 2013, Vol 18, Issue 12, p1
- ISSN
1083-3668
- Publication type
Article
- DOI
10.1117/1.JBO.18.12.126001