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- Title
Studies on 2-Ethyl-3-carbmethoxy-4-aryl-5-oxo-1,4,5,6,7,8-hexahydroquinoline Derivatives and Calcium Modulatory Activities.
- Authors
Şafak, Cihat; Doğan, Elvan; Erol, Kevser
- Abstract
Twelve new compounds having a 2-ethyl-3-carbmethoxy-4-aryl-5-oxo-1,4,5,6,7,8-hexahydroquinoline structure were synthesized, characterized and screened for their calcium modulatory activities. The calcium antagonistic activities of the compounds were investigated by tests performed on isolated rat ileum and lamb carotid artery. Compounds 1, 4, 8 and 9 showed considerable activity.
- Subjects
CALCIUM; CHEMICAL inhibitors; ILEUM; CAROTID artery; SMALL intestine; RATS
- Publication
Turkish Journal of Chemistry, 2006, Vol 30, Issue 1, p109
- ISSN
1300-0527
- Publication type
Article