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- Title
Tea crude extracts effectively inactivate severe acute respiratory syndrome coronavirus 2.
- Authors
Ishimoto, K.; Hatanaka, N.; Otani, S.; Maeda, S.; Xu, B.; Yasugi, M.; Moore, J.E.; Suzuki, M.; Nakagawa, S.; Yamasaki, S.
- Abstract
It is well known that black and green tea extracts, particularly polyphenols, have antimicrobial activity against various pathogenic microbes including viruses. However, there is limited data on the antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which emerged rapidly in China in late 2019 and which has been responsible for coronavirus disease 2019 (COVID‐19) pandemic globally. In this study, 20 compounds and three extracts were obtained from black and green tea and found that three tea extracts showed significant antiviral activity against SARS‐CoV‐2, whereby the viral titre decreased about 5 logs TCID50 per ml by 1·375 mg ml−1 black tea extract and two‐fold diluted tea bag infusion obtained from black tea when incubated at 25°C for 10 s. However, when concentrations of black and green tea extracts were equally adjusted to 344 µg ml−1, green tea extracts showed more antiviral activity against SARS‐CoV‐2. This simple and highly respected beverage may be a cheap and widely acceptable means to reduce SARS‐CoV‐2 viral burden in the mouth and upper gastrointestinal and respiratory tracts in developed as well as developing countries.
- Subjects
CHINA; GREEN tea; TEA extracts; COVID-19; PLANT extracts
- Publication
Letters in Applied Microbiology, 2022, Vol 74, Issue 1, p2
- ISSN
0266-8254
- Publication type
Article
- DOI
10.1111/lam.13591