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- Title
The Role of Pan-Immune-Inflammation Value in Determining the Severity of Coronary Artery Disease in NSTEMI Patients.
- Authors
Cetinkaya, Zeki; Kelesoglu, Saban; Tuncay, Aydin; Yilmaz, Yucel; Karaca, Yucel; Karasu, Mehdi; Secen, Ozlem; Cinar, Ahmet; Harman, Murat; Sahin, Seyda; Akin, Yusuf; Yavcin, Ozkan
- Abstract
Background: Even though medication and interventional therapy have improved the death rate for non-ST elevation myocardial infarction (NSTEMI) patients, these patients still have a substantial residual risk of cardiovascular events. Early identification of high-risk individuals is critical for improving prognosis, especially in this patient group. The focus of recent research has switched to finding new related indicators that can help distinguish high-risk patients. For this purpose, we examined the relationship between the pan-immune-inflammation value (PIV) and the severity of coronary artery disease (CAD) defined by the SYNTAX score (SxS) in NSTEMI patients. Methods: Based on the SxS, CAD patients were split into three groups. To evaluate the risk variables of CAD, multivariate logistic analysis was employed. Results: The PIV (odds ratio: 1.003; 95% CI: 1.001–1.005; p = 0.005) was found to be an independent predictor of a high SxS in the multivariate logistic regression analysis. Additionally, there was a positive association between the PIV and SxS (r: 0.68; p < 0.001). The PIV predicted the severe coronary lesion in the receiver-operating characteristic curve analysis with a sensitivity of 91% and specificity of 81.1%, using an appropriate cutoff value of 568.2. Conclusions: In patients with non-STEMI, the PIV, a cheap and easily measured laboratory variable, was substantially correlated with a high SxS and the severity of CAD.
- Subjects
CORONARY artery disease; MYOCARDIAL infarction; NON-ST elevated myocardial infarction; LOGISTIC regression analysis
- Publication
Journal of Clinical Medicine, 2024, Vol 13, Issue 5, p1295
- ISSN
2077-0383
- Publication type
Article
- DOI
10.3390/jcm13051295