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- Title
Colocalization of substance P and GABA in retinal ganglion cells: A computer-assisted visualization.
- Authors
Caruso, Daniel M.; Owczarzak, Michael T.; Pourcho, Roberta G.
- Abstract
Ganglion cells in the albino rat retina were retrogradely labeled with the fluorescent dye, diamidino-yellow, from the superior colliculus. Preembedding and postembedding immunocytochemical techniques were employed in conjunction with computer-assisted image processing to visualize SP- and GABA-immunoreactivity. Examination of flatmount and sectioned retinas revealed that approximately 3% of the ganglion cells projecting to the contralateral superior colliculus exhibit SP-immunoreactivity. Moreover, these cells were found to comprise a subpopulation of the GABA-immunoreactive cells projecting to the rat tectum.
- Publication
Visual Neuroscience, 1990, Vol 5, Issue 4, p389
- ISSN
0952-5238
- Publication type
Article
- DOI
10.1017/S095252380000047X