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- Title
Walking in the Light: How History of Physical Activity, Sunlight, and Vitamin D Account for Body Fat-A UK Biobank Study.
- Authors
Klinedinst, Brandon S.; Meier, Nathan F.; Larsen, Brittany; Wang, Yueying; Yu, Shan; Mochel, Jonathan P.; Le, Scott; Wolf, Tovah; Pollpeter, Amy; Pappas, Colleen; Wang, Qian; Allenspach, Karin; Wang, Li; Russell, Daniel; Bennett, David A.; Willette, Auriel A.
- Abstract
<bold>Objective: </bold>The high prevalence of vitamin D deficiency and obesity drives the need for successful strategies that elevate vitamin D levels, prevent adipogenesis, and stimulate lipolysis. This study provides a theoretical model to evaluate how physical activity (PA) and sunlight exposure influence serum vitamin D levels and regional adiposity. This study hypothesized a posteriori that sunlight is associated with undifferentiated visceral adiposity by increasing the ratio of brown to white adipose tissue.<bold>Methods: </bold>Using 10-year longitudinal data, accelerometry, a sun-exposure questionnaire, and regional adiposity quantified by dual-energy x-ray absorptiometry imaging, a structural-equation mediation model of growth curves was constructed with a data-driven methodology.<bold>Results: </bold>Sunlight and PA conjointly increased serum vitamin D. Changes in vitamin D levels partially mediated how sunlight and PA impacted adiposity in visceral and subcutaneous regions within a subjective PA model. In an objective PA model, vitamin D was a mediator for subcutaneous regions only. Interestingly, sunlight was associated with less adiposity in subcutaneous regions but greater adiposity in visceral regions.<bold>Conclusions: </bold>Sunlight and PA may increase vitamin D levels. For the first time, this study characterizes a positive association between sunlight and visceral adiposity. Further investigation and experimentation are necessary to clarify the physiological role of sunlight exposure on adipose tissue.
- Subjects
BODY composition; VITAMIN D; PHYSICAL activity; WHITE adipose tissue; BROWN adipose tissue
- Publication
Obesity (19307381), 2020, Vol 28, Issue 8, p1428
- ISSN
1930-7381
- Publication type
journal article
- DOI
10.1002/oby.22852