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- Title
APB Selectively Reduces Visual Responses in Goldfish to High Spatiotemporal Frequencies.
- Authors
DeMarco, Paul J.; Nussdorf, Jonathan D.; Brockman, Douglas A.; Powers, Maureen K.
- Abstract
Visual responses of goldfish to rotating square-wave gratings were recorded before and after intraocular injection of 2-amino-4-phosphonobutyric acid (APB). High doses of APB reduced the rate of optokinetic nystagmus (OKN) to a relatively high spatial frequency grating moving at a high temporal frequency. Responses to a low spatial frequency grating were not altered, nor were responses to the higher spatial frequency when it rotated slowly. The effects of APB were transient and lasted no longer than 3 d. We conclude that APB reduces OKN to high spatiotemporal frequencies in goldfish.
- Publication
Visual Neuroscience, 1989, Vol 2, Issue 1, p15
- ISSN
0952-5238
- Publication type
Article
- DOI
10.1017/S0952523800004272