We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Circadian rhythm and atherosclerosis (Review).
- Authors
Zhang, Zaiqiang; Yu, Bin; Wang, Xinan; Luo, Caiyun; Zhou, Tian; Zheng, Xiaxia; Ding, Jiawang
- Abstract
Atherosclerosis is the leading cause of morbidity and mortality worldwide. The underlying pathogenesis involves multiple metabolic disorders, endothelial dysfunction and a maladaptive immune response, and leads to chronic arterial wall inflammation. Numerous normal physiological activities exhibit daily rhythmicity, including energy metabolism, vascular function and inflammatory immunoreactions, and disrupted or misaligned circadian rhythms may promote the progression of atherosclerosis. However, the association between the circadian rhythm and atherosclerosis remains to be fully elucidated. In the present review, the effects of the circadian rhythm on atherosclerosis progression are discussed.
- Subjects
CIRCADIAN rhythms; ATHEROSCLEROSIS; ENDOTHELIUM diseases; PATHOLOGY; ENERGY metabolism; VASCULAR smooth muscle
- Publication
Experimental & Therapeutic Medicine, 2020, Vol 20, Issue 5, pN.PAG
- ISSN
1792-0981
- Publication type
Article
- DOI
10.3892/etm.2020.9224