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- Title
International Forum on Policies and Practice for Transfusion of ABO and RhD Non‐Identical Platelets: Summary.
- Authors
Cardigan, Rebecca; New, Helen V.; Estcourt, Lise; Zhiburt, Eugene; Dubey, Rounak; Bengtsson, Jesper; Jöud, Magnus; Castillo, Carlos; Cid, Joan; Lozano, Miquel; Gounder, Dhana; Flanagan, Peter; Morley, Sarah; Clarke, Gwen; Devine, Dana; Hindawi, Salwa; AlOtaibi, Aqeel; Bub, Carolina Bonnet; Kutner, Jose Mauro; Ikeda, Toshiyuki
- Abstract
The impact of platelet transfusion characteristics on posttransfusion platelet increments and clinical bleeding in patients with hypoproliferative thrombocytopenia. Labelled as high titre or low titre according to cut offs.</td></tr></tbody></table> ht The main reported effect of transfusion of ABO major incompatible platelets is a reduction in platelet count increment following transfusion, which appears to be a cumulative effect [1]. Transfusion of minor ABO incompatible platelets (where the suspending plasma of the platelet concentrate is not compatible with the ABO group of the recipient's red cells) has been associated with increased risk of haemolytic transfusion reactions. Transfusion of ABO major incompatible platelets (where the recipient has antibodies against the ABO group of the transfused platelets) has been shown to be associated with lower platelet count increments following transfusion [1], although this does not appear to translate to a difference in bleeding outcomes [2].
- Subjects
BLOOD transfusion reaction; NON-communicable diseases; BLOOD platelets; ABO blood group system; BLOOD group incompatibility
- Publication
Vox Sanguinis, 2022, Vol 117, Issue 1, p136
- ISSN
0042-9007
- Publication type
Article
- DOI
10.1111/vox.13129