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- Title
Reduction of foveal bulges and other anatomical changes in fellow eyes of patients with unilateral idiopathic macular hole without vitreomacular pathologic changes.
- Authors
Delas, Barbara; Julio, Gemma; Fernández-Vega, Álvaro; Casaroli-Marano, Ricardo; Nadal, Jeroni
- Abstract
Purpose: To compare the foveal characteristics in fellow eyes (FE) of patients with unilateral idiopathic macular hole without vitreomacular pathologic changes with eyes of healthy controls. Methods: Forty-seven FE and 52 eyes of 52 age- and sex-matched healthy controls were studied. Quantitative assessment of the dome-shaped appearance of the hyperreflective lines that represent external limiting membrane (ELM_bulge) and inner outer segment junctions (IS/OS_bulge) were made by optical coherence tomography (OCT) images. Inner retinal complex thickness (IRCT) was quantitatively assessed at 1000 and 2000 μm of the foveal center in nasal and temporal quadrants. Presence of alterations in the inner retinal outer layers and central foveal thickness (CFT) were also analyzed. Results: Significantly lower ELM_bulge ( p < 0.0001; Mann-Whitney test) and IS/OS_bulge ( p < 0.001; student t test) and higher cases with COST alterations, expressed as a diffuse line ( p < 0.006; Chi test) were found in FE than control eyes. IRCT were significantly reduced in FE at all the studied locations when comparing to control eyes ( p < 0.05; student t test), maintaining anatomical proportionality among locations. Conclusion: FE without pathologic vitreomacular interactions seems to present some central cone alterations that may be related to other causes than vitreomacular traction.
- Subjects
RETINAL degeneration; PATHOLOGY; OPTICAL coherence tomography; NASAL cavity; CONTROL groups
- Publication
Graefe's Archive of Clinical & Experimental Ophthalmology, 2017, Vol 255, Issue 11, p2141
- ISSN
0721-832X
- Publication type
Article
- DOI
10.1007/s00417-017-3765-z