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- Title
Synthesis and antibacterial activity of N,N′-diaryl-2-aryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides.
- Authors
Gein, V. L.; Levandovskaya, E. V.; Nosova, N. V.; Antonova, N. V.; Voronina, E. V.; Vakhrin, M. I.; Krivenko, A. P.
- Abstract
A series of N,N′-diaryl-2-aryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides have been synthesized by the reaction of N-arylamides of acetoacetic acid with aromatic aldehydes in the presence of piperidine. The structures of the products were determined by IR, PMR, and mass spectroscopy. Data on the antimicrobial activity of the synthesized compounds are presented.
- Subjects
ETHYL acetoacetate; ALDEHYDE reactivity; PIPERIDINE; MASS spectrometry; MICROBIAL sensitivity tests
- Publication
Pharmaceutical Chemistry Journal, 2007, Vol 41, Issue 12, p643
- ISSN
0091-150X
- Publication type
Article
- DOI
10.1007/s11094-008-0043-8