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- Title
RiboD: a comprehensive database for prokaryotic riboswitches.
- Authors
Mukherjee, Sumit; Mandal, Sukhen Das; Gupta, Nikita; Drory-Retwitzer, Matan; Barash, Danny; Sengupta, Supratim
- Abstract
Summary Riboswitches are cis-regulatory non-coding genomic segments that control the expression of downstream genes by undergoing conformational change upon ligand binding. We present a comprehensive database of prokaryotic riboswitches that allows the user to search for riboswitches using multiple criteria, extract information about riboswitch location and gene/operon it regulates. RiboD provides a very useful resource that can be utilized for the better understanding of riboswitch-based gene regulation in bacteria and archaea. Availability and implementation RiboD can be freely accessed on the web at http://ribod.iiserkol.ac.in/.
- Subjects
RIBOSWITCHES; LIGAND binding (Biochemistry); GENETIC regulation; BACTERIAL genes; DATABASES
- Publication
Bioinformatics, 2019, Vol 35, Issue 18, p3541
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btz093