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- Title
The effect of bio-converted polyunsaturated fatty acids on the oxidation of TAG containing highly unsaturated fatty acids.
- Authors
Young-Mi Kim; Geon-Ho Lee; Young-Geun Yeo; In-Hwan Kim; Kazuo Miyashita; Ching Hou; Sun-Chul Kang; Hak-Ryul Kim
- Abstract
Microbial modification of vegetable fatty acids can often lead to special changes in their structure and in biological function. A bacterial strain, Pseudomonas aeruginosa PR3, is known to carry out multiple hydroxylations on polyunsaturated fatty acids containing 1,4- cis, cis diene structural units, resulting in antibacterial activity. In this paper, in an effort to understand the overall mechanism involved in the varied biological functions of the complicated metabolites of bio-converted polyunsaturated fatty acids, we performed bioconversion of several polyunsaturated fatty acids using PR3, and determined their oxidative activities against fish oil. Bio-converted linoleic acid, eicosapentanoic acid, and docosahexanoic acid promoted effectively oxidation of fish oil. It is assumed that this oxidative effect could plausibly play an important role in the antimicrobial function of these bio-converted fatty acids.
- Subjects
UNSATURATED fatty acids; FATTY acids; ALKENES; OXIDATION; METABOLITES; BIOMOLECULES
- Publication
Journal of Industrial Microbiology & Biotechnology, 2006, Vol 33, Issue 1, p17
- ISSN
1367-5435
- Publication type
Article
- DOI
10.1007/s10295-005-0037-4