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- Title
EVALUATION OF THE ANTIOXIDANT AND ANTIBACTERIAL POTENTIAL OF BIOACTIVE COMPOUNDS FROM AJUGA REPTANS EXTRACTS.
- Authors
TOIU, ANCA; VLASE, LAURIAN; GHELDIU, ANA MARIA; VODNAR, DAN; ONIGA, ILIOARA
- Abstract
The aim of this study was to evaluate the polyphenols and iridoids from Ajuga reptans (Lamiaceae) flower extracts, and their antioxidant and antibacterial activities. Total phenolic content (TPC), total flavonoid content (TFC), total anthocyanin content (TAC) and HPLC/UV/MS were employed for the identification and quantification of polyphenolic compounds. Total iridoid contents (TIC) were determined through a colorimetric method. The bioactive compounds were found in higher quantities in the ethanol extracts. Caffeic, p-coumaric and ferulic acids, quercitrin, luteolin and apigenin were identified by LC/MS in all samples. The antioxidant effects were evaluated by DPPH assay and TPC. A. reptans ethanol extract exhibited a higher antioxidant activity than the methanol extract, and a positive correlation between the antioxidant properties and the concentration of polyphenols was observed. The antimicrobial activity was evaluated by the use of dilution assays; the minimal inhibitory concentration and the minimal bactericidal concentration values were determined. These results indicate that A. reptans flowers contain active compounds with antioxidant and antibacterial potential.
- Subjects
ANTIOXIDANTS; AJUGA; ANTIBACTERIAL agents; BIOACTIVE compounds; PLANT extracts
- Publication
Farmacia, 2017, Vol 65, Issue 3, p351
- ISSN
0014-8237
- Publication type
Article