We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Transjugular intrahepatic portosystemic shunt through left branch versus right branch of portal vein: a meta-analysis.
- Authors
Zuo, Kai; Wang, Cong; Wang, Jun; Xia, Feng-Fei; Song, Tao
- Abstract
Purpose: To compare the clinical outcomes between patients that underwent transjugular intrahepatic portosystemic shunt (TIPS) via the left and right portal veins (PVs). Materials and methods: All relevant studies in the Pubmed, Embase, and Cochrane Library databases published as of June 2020 were identified by searching, after which RevMan v5.3 was used to conduct the present meta-analysis. Relevant endpoint data were extracted from each study, related to postoperative hepatic encephalopathy (HE) rates, TIPS dysfunction, re-bleeding, and mortality. Results: A total of eight studies were identified as being relevant for inclusion in this meta-analysis. These studies included 2592 total patients suffering from liver cirrhosis that underwent TIPS treatment via the left (n = 1500) or right (n = 1092) PVs. Rates of postoperative HE were significantly lower in the left PV group relative to the right PV group (5.7% vs. 18.1%, OR 0.19; P < 0.00001), as were rates of TIPS dysfunction (8.1% vs. 16.5%, OR 0.41; P < 0.00001). In contrast, the rates of re-bleeding did not differ significantly between these groups (12.0% vs. 14.9%, OR 0.76; P = 0.11), nor did mortality rates (30.9% vs. 31.0%, OR 0.85, P = 0.22). We did not detect any significant heterogeneity among included studies for any analyzed endpoints, nor was any risk of publication bias pertaining to these studies detected through the use of funnel plots. Conclusions: TIPS conducted via the left PV was associated with decreased rates of postoperative HE and TIPS dysfunction relative to TIPS conducted via the right PV.
- Subjects
PORTAL vein; HEPATIC portal system; HEPATIC encephalopathy; CIRRHOSIS of the liver; INTRAHEPATIC bile ducts; CEREBROSPINAL fluid shunts
- Publication
Abdominal Radiology, 2021, Vol 46, Issue 4, p1718
- ISSN
2366-004X
- Publication type
Article
- DOI
10.1007/s00261-020-02789-9