We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Adaptations in Capillarization and Citrate Synthase Activity in Response to Endurance Training in Older and Young Men.
- Authors
Murias, Juan M.; Kowalchuk, John M.; Ritchie, Darmyn; Hepple, Russell T.; Doherty, Timothy J.; Paterson, Donald H.
- Abstract
The time-course of adaptation in cardiorespiratory fitness, measures of capillarization, and citrate synthase (CS) activity were examined in seven older (O; 69 ± 7 years) and seven young (Y; 22 ± 1 years) men pre-, mid-, and posttraining during a 12-week endurance training program. Training was performed on a cycle ergometer three times per week for 45 minutes at ∼70% of maximal VO2 (VO2max). VO2max and maximal cardiac output increased similarly from pre- to posttraining in O and Y (p < .05), and maximal a-vO2diff was greater (p < .05) posttraining in O and Y. CS was elevated at mid- and posttraining compared with pretraining in both O and Y (p < .05). Indices of capillarization increased 30%–40% in O and 20%–30% in Y and were elevated at posttraining compared with pre- and midtraining in both groups (p < .05). This study showed that both O and Y undertaking similar endurance training displayed capillary angiogenesis and improved mitochondrial respiratory capacity.
- Subjects
PHYSIOLOGICAL adaptation; CAPILLARIES; CITRATE synthase; EXERCISE physiology; OLDER men; YOUNG men
- Publication
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2011, Vol 66A, Issue 9, p957
- ISSN
1079-5006
- Publication type
Article
- DOI
10.1093/gerona/glr096