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- Title
Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe<sub>2</sub>O)<sub>2</sub>H}(PMe<sub>2</sub>OH)]: A Review.
- Authors
Cadierno, Victorio
- Abstract
The air-stable hydride-platinum(II) complex [PtH{(PMe2O)2H}(PMe2OH)], reported by Parkins and co-workers in 1995, is the most versatile catalyst currently available for the hydration of C=N bonds. It features remarkable activity under relatively mild conditions and exceptionally high functional group compatibility, facts that have allowed the implementation of this complex in the synthesis of a large number of structurally complex, biologically active molecules and natural products. In this contribution, synthetic applications of the Parkins catalyst are reviewed.
- Subjects
PLATINUM compound synthesis; CATALYTIC hydration; NITRILE synthesis
- Publication
Applied Sciences (2076-3417), 2015, Vol 5, Issue 3, p380
- ISSN
2076-3417
- Publication type
Article
- DOI
10.3390/app5030380