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- Title
Evasion of Influenza A Viruses from Innate and Adaptive Immune Responses.
- Authors
van de Sandt,, Carolien E.; Kreijtz, Joost H. C. M.; Rimmelzwaan, Guus F.
- Abstract
The influenza A virus is one of the leading causes of respiratory tract infections in humans. Upon infection with an influenza A virus, both innate and adaptive immune responses are induced. Here we discuss various strategies used by influenza A viruses to evade innate immune responses and recognition by components of the humoral and cellular immune response, which consequently may result in reduced clearing of the virus and virus-infected cells. Finally, we discuss how the current knowledge about immune evasion can be used to improve influenza A vaccination strategies.
- Subjects
INFLUENZA A virus; RESPIRATORY infections; PREVENTION of communicable diseases; VACCINATION; IMMUNOLOGY
- Publication
Viruses (1999-4915), 2012, Vol 4, Issue 9, p1438
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v4091438