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- Title
How HIV Takes Advantage of the Cytoskeleton in Entry and Replication.
- Authors
Stolp, Bettina; Fackler, Oliver T.
- Abstract
The host cell cytoskeleton plays a key role in the life cycle of viral pathogens whose propagation depends on mandatory intra cellular steps. Accordingly, also the human immunodeficiency virus type 1 (HIV-1) has evolved strategies to exploit and modulate in particular the actin cytoskeleton for its purposes. This review will recapitulate recent findings on how HIV-1 hijacks the cytoskeleton to facilitate entry into, transport within and egress from host cells as well as to commandeer communication of infected with uninfected bystander cells.
- Subjects
HIV; ACTIN; CYTOSKELETON; PATHOGENIC microorganisms; CELL motility
- Publication
Viruses (1999-4915), 2011, Vol 3, Issue 4, p293
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v3040293