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Mega-dose sodium ascorbate: a pilot, single-dose, physiological effect, double-blind, randomized, controlled trial.
Published in:
Critical Care, 2023, v. 27, n. 1, p. 1, doi. 10.1186/s13054-023-04644-x
By:
- Yanase, Fumitaka;
- Spano, Sofia;
- Maeda, Akinori;
- Chaba, Anis;
- Naorungroj, Thummaporn;
- Ow, Connie Pei Chen;
- Lankadeva, Yugeesh R.;
- May, Clive N.;
- Betrie, Ashenafi H.;
- Lane, Darius J. R.;
- Eastwood, Glenn M.;
- Plummer, Mark P.;
- Bellomo, Rinaldo
Publication type:
Article
Continuous bladder urinary oxygen tension as a new tool to monitor medullary oxygenation in the critically ill.
Published in:
Critical Care, 2022, v. 26, n. 1, p. 1, doi. 10.1186/s13054-022-04230-7
By:
- Hu, Raymond T.;
- Lankadeva, Yugeesh R.;
- Yanase, Fumitake;
- Osawa, Eduardo A.;
- Evans, Roger G.;
- Bellomo, Rinaldo
Publication type:
Article
Dynamic responses of renal oxygenation at the onset of cardiopulmonary bypass in sheep and man.
Published in:
Perfusion, 2022, v. 37, n. 6, p. 624, doi. 10.1177/02676591211013640
By:
- Evans, Roger G;
- Cochrane, Andrew D;
- Hood, Sally G;
- Iguchi, Naoya;
- Marino, Bruno;
- Bellomo, Rinaldo;
- McCall, Peter R;
- Okazaki, Nobuki;
- Smith, Julian A;
- Zhu, Michael ZL;
- Ngo, Jennifer P;
- Noe, Khin M;
- Martin, Andrew;
- Thrift, Amanda G;
- Lankadeva, Yugeesh R;
- May, Clive N
Publication type:
Article
Renal Cortical Perfusion, Measured by Superb Microvascular Imaging, during Infusion of Norepinephrine in Experimental Cardiopulmonary Bypass.
Published in:
2019
By:
- Iguchi, Naoya;
- Lankadeva, Yugeesh R;
- Evans, Roger G;
- Cochrane, Andrew D;
- Marino, Bruno;
- Bellomo, Rinaldo;
- May, Clive N
Publication type:
journal article
Effects of sodium-glucose transporter-2 inhibition on systemic hemodynamics, renal function, and intra-renal oxygenation in sepsis-associated acute kidney injury.
Published in:
Intensive Care Medicine Experimental, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40635-024-00647-2
By:
- Hulst, Abraham H.;
- Ow, Connie P. C.;
- May, Clive N.;
- Hood, Sally H.;
- Plummer, Mark P.;
- Hermanides, Jeroen;
- van Raalte, Daniël H.;
- Deane, Adam M.;
- Bellomo, Rinaldo;
- Lankadeva, Yugeesh R.
Publication type:
Article
Splanchnic sympathetic nerve denervation improves bacterial clearance and clinical recovery in established ovine Gram-negative bacteremia.
Published in:
Intensive Care Medicine Experimental, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40635-023-00530-6
By:
- Peiris, Rachel M.;
- May, Clive N.;
- Booth, Lindsea C.;
- McAllen, Robin M.;
- McKinley, Michael J.;
- Hood, Sally;
- Martelli, Davide;
- Bellomo, Rinaldo;
- Lankadeva, Yugeesh R.
Publication type:
Article
Effects of changes in inspired oxygen fraction on urinary oxygen tension measurements.
Published in:
Intensive Care Medicine Experimental, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40635-022-00479-y
By:
- Osawa, Eduardo A.;
- Cutuli, Salvatore L.;
- Yanase, Fumitaka;
- Iguchi, Naoya;
- Bitker, Laurent;
- Maciel, Alexandre T.;
- Lankadeva, Yugeesh R.;
- May, Clive N.;
- Evans, Roger G.;
- Eastwood, Glenn M.;
- Bellomo, Rinaldo
Publication type:
Article
Effects of selective β1-adrenoceptor blockade on cardiovascular and renal function and circulating cytokines in ovine hyperdynamic sepsis.
Published in:
Critical Care, 2014, v. 18, n. 6, p. 610, doi. 10.1186/s13054-014-0610-1
By:
- Calzavacca, Paolo;
- Lankadeva, Yugeesh R.;
- Bailey, Simon R.;
- Bailey, Michael;
- Bellomo, Rinaldo;
- May, Clive N.
Publication type:
Article
Sepsis‐induced acute kidney injury: A disease of the microcirculation.
Published in:
Microcirculation, 2019, v. 26, n. 2, p. N.PAG, doi. 10.1111/micc.12483
By:
- Ma, Shuai;
- Evans, Roger G.;
- Iguchi, Naoya;
- Tare, Marianne;
- Parkington, Helena C.;
- Bellomo, Rinaldo;
- May, Clive N.;
- Lankadeva, Yugeesh R.
Publication type:
Article
Acute kidney injury in sepsis.
Published in:
2017
By:
- Bellomo, Rinaldo;
- Kellum, John;
- Ronco, Claudio;
- Wald, Ron;
- Martensson, Johan;
- Maiden, Matthew;
- Bagshaw, Sean;
- Glassford, Neil;
- Lankadeva, Yugeesh;
- Vaara, Suvi;
- Schneider, Antoine;
- Kellum, John A;
- Bagshaw, Sean M;
- Glassford, Neil J;
- Vaara, Suvi T
Publication type:
journal article
Targeting Oxidative Stress in Septic Acute Kidney Injury: From Theory to Practice.
Published in:
Journal of Clinical Medicine, 2021, v. 10, n. 17, p. 3798, doi. 10.3390/jcm10173798
By:
- Ow, Connie P. C.;
- Trask-Marino, Anton;
- Betrie, Ashenafi H.;
- Evans, Roger G.;
- May, Clive N.;
- Lankadeva, Yugeesh R.
Publication type:
Article
Differential responses of cerebral and renal oxygenation to altered perfusion conditions during experimental cardiopulmonary bypass in sheep.
Published in:
Clinical & Experimental Pharmacology & Physiology, 2024, v. 51, n. 4, p. 1, doi. 10.1111/1440-1681.13852
By:
- Evans, Roger G.;
- Cochrane, Andrew D.;
- Hood, Sally G.;
- Marino, Bruno;
- Iguchi, Naoya;
- Bellomo, Rinaldo;
- McCall, Peter R.;
- Okazaki, Nobuki;
- Jufar, Alemayehu H.;
- Miles, Lachlan F.;
- Furukawa, Taku;
- Ow, Connie P. C.;
- Raman, Jaishankar;
- May, Clive N.;
- Lankadeva, Yugeesh R.
Publication type:
Article
Therapeutic potential of megadose vitamin C to reverse organ dysfunction in sepsis and COVID‐19.
Published in:
British Journal of Pharmacology, 2021, v. 178, n. 19, p. 3864, doi. 10.1111/bph.15579
By:
- May, Clive N.;
- Bellomo, Rinaldo;
- Lankadeva, Yugeesh R.
Publication type:
Article
Emerging benefits and drawbacks of α<sub>2</sub> -adrenoceptor agonists in the management of sepsis and critical illness.
Published in:
2021
By:
- Lankadeva, Yugeesh R.;
- Shehabi, Yahya;
- Deane, Adam M.;
- Plummer, Mark P.;
- Bellomo, Rinaldo;
- May, Clive N.
Publication type:
journal article
Improvement in Renal Hemodynamics following Combined Angiotensin II Infusion and AT1R Blockade in Aged Female Sheep following Fetal Unilateral Nephrectomy.
Published in:
PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068036
By:
- Singh, Reetu R.;
- Lankadeva, Yugeesh R.;
- Denton, Kate M.;
- Moritz, Karen M.
Publication type:
Article
Blunted Sodium Excretion in Response to a Saline Load in 5 Year Old Female Sheep Following Fetal Uninephrectomy.
Published in:
PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047528
By:
- Lankadeva, Yugeesh R.;
- Singh, Reetu R.;
- Hilliard, Lucinda M.;
- Moritz, Karen M.;
- Denton, Kate M.
Publication type:
Article
Increased Cardiovascular and Renal Risk Is Associated with Low Nephron Endowment in Aged Females: An Ovine Model of Fetal Unilateral Nephrectomy.
Published in:
PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042400
By:
- Singh, Reetu R.;
- Jefferies, Andrew J.;
- Lankadeva, Yugeesh R.;
- Lombardo, Paul;
- Schneider-Kolsky, Michal;
- Hilliard, Lucinda;
- Denton, Kate M.;
- Moritz, Karen M.;
- Ashton, Nick
Publication type:
Article
Renal arterial infusion of tempol prevents medullary hypoperfusion, hypoxia, and acute kidney injury in ovine Gram‐negative sepsis.
Published in:
Acta Physiologica, 2023, v. 239, n. 1, p. 1, doi. 10.1111/apha.14025
By:
- Betrie, Ashenafi H.;
- Ma, Shuai;
- Ow, Connie P. C.;
- Peiris, Rachel M.;
- Evans, Roger G.;
- Ayton, Scott;
- Lane, Darius J. R.;
- Southon, Adam;
- Bailey, Simon R.;
- Bellomo, Rinaldo;
- May, Clive N.;
- Lankadeva, Yugeesh R.
Publication type:
Article
The effects of recruitment of renal functional reserve on renal cortical and medullary oxygenation in non‐anesthetized sheep.
Published in:
Acta Physiologica, 2023, v. 237, n. 4, p. 1, doi. 10.1111/apha.13919
By:
- Jufar, Alemayehu H.;
- Evans, Roger G.;
- May, Clive N.;
- Hood, Sally G.;
- Betrie, Ashenafi H.;
- Trask‐Marino, Anton;
- Bellomo, Rinaldo;
- Lankadeva, Yugeesh R.
Publication type:
Article
Influence of moderate hypothermia on renal and cerebral haemodynamics and oxygenation during experimental cardiopulmonary bypass in sheep.
Published in:
Acta Physiologica, 2022, v. 236, n. 1, p. 1, doi. 10.1111/apha.13860
By:
- Jufar, Alemayehu H.;
- May, Clive N.;
- Evans, Roger G.;
- Cochrane, Andrew D.;
- Marino, Bruno;
- Hood, Sally G.;
- McCall, Peter R.;
- Bellomo, Rinaldo;
- Lankadeva, Yugeesh R.
Publication type:
Article
Reversal of renal tissue hypoxia during experimental cardiopulmonary bypass in sheep by increased pump flow and arterial pressure.
Published in:
Acta Physiologica, 2021, v. 231, n. 4, p. 1, doi. 10.1111/apha.13596
By:
- Lankadeva, Yugeesh R.;
- Evans, Roger G.;
- Cochrane, Andrew D.;
- Marino, Bruno;
- Hood, Sally G.;
- McCall, Peter R.;
- Iguchi, Naoya;
- Bellomo, Rinaldo;
- May, Clive N.
Publication type:
Article
Influence of blood haemoglobin concentration on renal haemodynamics and oxygenation during experimental cardiopulmonary bypass in sheep.
Published in:
Acta Physiologica, 2021, v. 231, n. 3, p. 1, doi. 10.1111/apha.13583
By:
- Lankadeva, Yugeesh R.;
- May, Clive N.;
- Cochrane, Andrew D.;
- Marino, Bruno;
- Hood, Sally G.;
- McCall, Peter R.;
- Okazaki, Nobuki;
- Bellomo, Rinaldo;
- Evans, Roger G.
Publication type:
Article
Factors that confound the prediction of renal medullary oxygenation and risk of acute kidney injury from measurement of bladder urine oxygen tension.
Published in:
Acta Physiologica, 2019, v. 227, n. 1, p. N.PAG, doi. 10.1111/apha.13294
By:
- Ngo, Jennifer P.;
- Lankadeva, Yugeesh R.;
- Zhu, Michael Z. L.;
- Martin, Andrew;
- Kanki, Monica;
- Cochrane, Andrew D.;
- Smith, Julian A.;
- Thrift, Amanda G.;
- May, Clive N.;
- Evans, Roger G.
Publication type:
Article
Effects of furosemide, acetazolamide and amiloride on renal cortical and medullary tissue oxygenation in non‐anaesthetised healthy sheep.
Published in:
Experimental Physiology, 2024, v. 109, n. 5, p. 766, doi. 10.1113/EP091479
By:
- Ow, Connie P. C.;
- Okazaki, Nobuki;
- Iguchi, Naoya;
- Peiris, Rachel M.;
- Evans, Roger G.;
- Hood, Sally G.;
- May, Clive N.;
- Bellomo, Rinaldo;
- Lankadeva, Yugeesh R.
Publication type:
Article
Cerebrospinal fluid and plasma ascorbate concentrations following subarachnoid haemorrhage.
Published in:
Critical Care & Resuscitation, 2023, v. 25, n. 4, p. 175, doi. 10.1016/j.ccrj.2023.10.003
By:
- Turner, Natasha;
- Farrow, Brodie;
- Betrie, Ashenafi H.;
- Finnis, Mark E.;
- Lankadeva, Yugeesh R.;
- Sharman, Jeremy;
- Tan, Patrick;
- Abdelhamid, Yasmine Ali;
- Deane, Adam M.;
- Plummer, Mark P.
Publication type:
Article
LOVIT or leave it: The vitamin C debate continues.
Published in:
Critical Care & Resuscitation, 2023, v. 25, n. 2, p. 63, doi. 10.1016/j.ccrj.2023.05.001
By:
- Lankadeva, Yugeesh R.;
- Lane, Darius JR.;
- Ow, Connie P. C.;
- Story, David A.;
- Plummer, Mark P.;
- May, Clive N.
Publication type:
Article
Cytokine and lipid metabolome effects of low-dose acetylsalicylic acid in critically ill patients with systemic inflammation: a pilot, feasibility, multicentre, randomised, placebo-controlled trial.
Published in:
Critical Care & Resuscitation, 2020, v. 22, n. 3, p. 227, doi. 10.1016/s1441-2772(23)00390-3
By:
- Cioccari, Luca;
- Luethi, Nora;
- Thy Duong;
- Ryan, Eileen;
- Cutuli, Salvatore L.;
- Lloyd-Donald, Patryck;
- Eastwood, Glenn M.;
- Peck, Leah;
- Young, Helen;
- Vaara, Suvi T.;
- French, Craig J.;
- Orford, Neil;
- Dwivedi, Jyotsna;
- Lankadeva, Yugeesh R.;
- Bailey, Michael;
- Reid, Gavin E.;
- Bellomo, Rinaldo
Publication type:
Article
Differential effects of isotonic and hypotonic 4% albumin solution on intracranial pressure and renal perfusion and function.
Published in:
Critical Care & Resuscitation, 2018, v. 20, n. 1, p. 48, doi. 10.1016/s1441-2772(23)00732-9
By:
- Iguchi, Naoya;
- Kosaka, Junko;
- Bertolini, Joseph;
- May, Clive N.;
- Lankadeva, Yugeesh R.;
- Bellomo, Rinaldo
Publication type:
Article
Sympathetic nerves control bacterial clearance.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72008-4
By:
- Lankadeva, Yugeesh R.;
- May, Clive N.;
- McKinley, Michael J.;
- Neeland, Melanie R.;
- Ma, Shuai;
- Hocking, Dianna M.;
- Robins-Browne, Roy;
- Bedoui, Sammy;
- Farmer, David G. S.;
- Bailey, Simon R.;
- Martelli, Davide;
- McAllen, Robin M.
Publication type:
Article
Vancomycin and Gentamicin Removal with the HA380 Cartridge during Experimental Hemoadsorption.
Published in:
Blood Purification, 2023, v. 52, n. 11/12, p. 880, doi. 10.1159/000534108
By:
- Furukawa, Taku;
- Lankadeva, Yugeesh;
- Baldwin, Ian Charles;
- Ow, Pei Chen Connie;
- Hood, Sally;
- May, Clive;
- Bellomo, Rinaldo
Publication type:
Article
Effect of Furosemide on Urinary Oxygenation in Patients with Septic Shock.
Published in:
Blood Purification, 2019, v. 48, n. 4, p. 336, doi. 10.1159/000501512
By:
- Osawa, Eduardo Atsushi;
- Cutuli, Salvatore Lucio;
- Bitker, Laurent;
- Canet, Emmanuel;
- Cioccari, Luca;
- Iguchi, Naoya;
- Lankadeva, Yugeesh R.;
- Eastwood, Glenn M.;
- Evans, Roger G.;
- May, Clive N.;
- Bellomo, Rinaldo
Publication type:
Article
Combatting Sepsis, the Biggest Killer in Intensive Care Units.
Published in:
AQ: Australian Quarterly, 2024, v. 95, n. 3, p. 38
By:
- LANKADEVA, YUGEESH;
- WRIGHT, HAYDN;
- PLUMMER, MARK
Publication type:
Article

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