We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The immunopathology of canine vector-borne diseases.
- Authors
Day, Michael J.
- Abstract
The canine vector-borne infectious diseases (CVBDs) are an emerging problem in veterinary medicine and the zoonotic potential of many of these agents is a significant consideration for human health. The successful diagnosis, treatment and prevention of these infections is dependent upon firm understanding of the underlying immunopathology of the diseases in which there are unique tripartite interactions between the microorganism, the vector and the host immune system. Although significant advances have been made in the areas of molecular speciation and the epidemiology of these infections and their vectors, basic knowledge of the pathology and immunology of the diseases has lagged behind. This review summarizes recent studies of the pathology and host immune response in the major CVBDs (leishmaniosis, babesiosis, ehrlichiosis, hepatozoonosis, anaplasmosis, bartonellosis and borreliosis). The ultimate application of such immunological investigation is the development of effective vaccines. The current commercially available vaccines for canine leishmaniosis, babesiosis and borreliosis are reviewed.
- Subjects
IMMUNOPATHOLOGY; VETERINARY medicine; ZOONOSES; VERRUGA peruana; BABESIOSIS
- Publication
Parasites & Vectors, 2011, Vol 4, Issue 1, p48
- ISSN
1756-3305
- Publication type
Article
- DOI
10.1186/1756-3305-4-48