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- Title
Survival of AIDS-related diffuse large B-cell lymphoma, Burkitt lymphoma, and plasmablastic lymphoma in the German HIV Lymphoma Cohort.
- Authors
Schommers, Philipp; Hentrich, Marcus; Hoffmann, Christian; Gillor, Daniel; Zoufaly, Alexander; Jensen, Björn; Bogner, Johannes R.; Thoden, Jan; Wasmuth, Jan‐Christian; Wolf, Timo; Oette, Mark; Müller, Markus; Esser, Stefan; Vehreschild, Jörg J.; Fätkenheuer, Gerd; Wyen, Christoph
- Abstract
Overall survival ( OS) of patients with acquired immunodeficiency syndrome ( AIDS)-related Burkitt lymphoma ( BL), diffuse large B-cell lymphoma ( DLBCL) and plasmablastic lymphoma ( PBL) was analysed in the German AIDS-related-Lymphoma-Cohort-Study. Of 291 patients prospectively included between January 2005 and December 2012, 154 had DLBCL, 103 BL and 34 PBL. Two-year OS rates were similar between BL (69%) and DLBCL patients (63%) but lower for PBL patients (43%). Intermediate (Hazard ratio [ HR] 4·1 95% confidence interval [ CI] 1·98-8·49) or high ( HR 4·92 95% CI 2·1-11·61) International Prognostic Index, bone marrow involvement ( HR 1·69 95% CI 1·00-2·84) and PBL histology ( HR 2·24 95% CI 1·24-4·03) were independent predictors of mortality.
- Subjects
GERMANY; DIFFUSE large B-cell lymphomas; AIDS-related lymphoma; BURKITT'S lymphoma; SURVIVAL analysis (Biometry); CANCER invasiveness; HIV-positive persons; PUBLIC health; PATIENTS
- Publication
British Journal of Haematology, 2015, Vol 168, Issue 6, p806
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1111/bjh.13221