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- Title
Synthesis of Chromen-2-one, Pyrano[3,4-c]chromene and Pyridino[3,4-c]chromene Derivatives as Potent Antimicrobial Agents.
- Authors
Fouad, Sawsan A.; Hessein, Sadia A.; Abbas, Samir Y.; Farrag, Amel M.; Ammar, Yousry A.
- Abstract
In an attempt for development of new antimicrobial agents; new series of chromen-2-one, pyrano[3,4-c]chromene and pyridino[3,4- c]chromene derivatives bearing a diazo moiety were synthesized. Chromen-2-one derivatives were synthesized via treatment of 5-(aryldiazo) salicylaldehyde with different type of active methylene derivatives. Pyrano[3,4-c]chromene and pyridino[3,4-c]chromene derivatives were synthesized via treatment of chromen-2-one derivatives with another active methylene derivatives. The synthesized compounds were evaluated for their expected antimicrobial activity; where, the majority of these compounds showed potent antibacterial and antifungal activities against the tested strains of bacteria and fungi.
- Subjects
CHEMICAL synthesis; ANTIBACTERIAL agents; ANTINEOPLASTIC agents; CHEMICAL reactions; X-ray diffraction
- Publication
Croatica Chemica Acta, 2018, Vol 91, Issue 1, p99
- ISSN
0011-1643
- Publication type
Article
- DOI
10.5562/cca3266