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- Title
Pleomorphic adenoma with squamous and appendageal metaplasia mimicking mucoepidermoid carcinoma on cytology.
- Authors
Batrani, Meenakshi; Kaushal, Manju; Sen, A. K.; Yadav, Rajbala; Chaturvedi, N. K.
- Abstract
Background: Histological diversity is the hallmark of pleomorphic adenoma, the most common salivary gland tumor. It may cause dificulty in cytological interpretation, due to limited and selective sampling. Case presentation: A 16-year-old female patient presented with right cheek swelling. Fine needle aspiration cytology showed squamous cells, basaloid cells, and foamy cells, along with extra-cellular keratin and foreign body giant cells. Characteristic metachromatic ibrillary chondromyxoid stroma, which is usually seen in pleomorphic adenoma, was not seen in the aspirate. A diagnosis of mucoepidermoid carcinoma was given on cytology. Subsequent resection revealed an encapsulated pleomorphic adenoma, with extensive squamous metaplasia and appendageal differentiation on histology. Conclusion: This case illustrates that pleomorphic adenoma with squamous metaplasia presents a potential for misinterpretation as mucoepidermoid carcinoma on cytology. We discuss the various pitfalls and the features that are helpful in distinguishing these two lesions.
- Subjects
METAPLASIA; SALIVARY gland cancer; CYTOLOGY; HISTOPATHOLOGY; TEENAGE girls; EDEMA; NEEDLE biopsy; DISEASES
- Publication
CytoJournal, 2009, Vol 6, Issue 1, p1
- ISSN
0974-5963
- Publication type
Article
- DOI
10.4103/1742-6413.45496