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- Title
A modified single-armed microsurgical vasoepididymostomy for epididymal obstructive azoospermia: intraoperative choice and postoperative consideration.
- Authors
Liu, Nachuan; Li, Peng; Zhi, Erlei; Yao, Chencheng; Yang, Chao; Zhao, Liangyu; Tian, Ruhui; Chen, Huixing; Huang, Yuhua; Yu, Yuexin; Li, Zheng
- Abstract
<bold>Background: </bold>To evaluate the clinical outcomes and the duration required for the sperm to return to the ejaculate after a modified single-armed 2-suture longitudinal intussusception vasoepididymostomy (SA-LIVE).<bold>Methods: </bold>From March 2015 to December 2018, 134 patients with epididymal obstruction azoospermia underwent the modified single-armed vasoepididymostomy at Shanghai General Hospital. The outcomes and clinical findings were documented and evaluated. The mean follow-up period was 17 (range: 3-36) months.<bold>Results: </bold>Patency was assessed by the return of sperm in the ejaculate. The overall patency rate was 55.2%, and the patency rates were 58.9, 40.7, 36.4, and 58.9% for bilateral surgery, unilateral surgery, proximal anastomosis, and distal anastomosis, respectively. The average time to achieve patency was 4.11 ± 2.74 months. In the first 6 months, 87.8% (65/74) patency patients reported sperm in the ejaculate. The overall pregnancy rate was 40.9% (29/66) at the follow-up of 3-36 months, and the natural pregnancy rate was 30.3% (20/66). The natural pregnancy rate was 32.1% post-bilateral surgery and 33.3% for the site of distal anastomosis; surprisingly, it was 0% for the site of proximal anastomosis.<bold>Conclusion: </bold>Modified SA-LIVE is safe and may achieve favorable patency and pregnancy rates. When double-armed sutures are not accessible, single-armed may be preferable. The expected patency time was within 1 year. Moreover, because of the low natural pregnancy rate for proximal anastomosis, sperm banking is preferred to SA-LIVE.
- Subjects
SHANGHAI (China); SPERM banks; PREGNANCY; MALE infertility; SPERMATOZOA; VAS deferens surgery; SURGICAL therapeutics; SURGICAL anastomosis; BIRTH rate; MICROSURGERY; MEN; INFERTILITY; TREATMENT effectiveness; QUESTIONNAIRES; RESEARCH funding; EPIDIDYMIS; UROLOGICAL surgery; LONGITUDINAL method
- Publication
BMC Urology, 2020, Vol 20, Issue 1, p1
- ISSN
1471-2490
- Publication type
journal article
- DOI
10.1186/s12894-020-00692-5