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An autocrine ActivinB mechanism drives TGFβ/Activin signaling in Group 3 medulloblastoma.
Published in:
EMBO Molecular Medicine, 2019, v. 11, n. 8, p. N.PAG, doi. 10.15252/emmm.201809830
By:
- Morabito, Morgane;
- Larcher, Magalie;
- Cavalli, Florence MG;
- Foray, Chloé;
- Forget, Antoine;
- Mirabal‐Ortega, Liliana;
- Andrianteranagna, Mamy;
- Druillennec, Sabine;
- Garancher, Alexandra;
- Masliah‐Planchon, Julien;
- Leboucher, Sophie;
- Debalkew, Abel;
- Raso, Alessandro;
- Delattre, Olivier;
- Puget, Stéphanie;
- Doz, François;
- Taylor, Michael D;
- Ayrault, Olivier;
- Bourdeaut, Franck;
- Eychène, Alain
Publication type:
Article
Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice.
Published in:
EMBO Molecular Medicine, 2011, v. 3, n. 1, p. 50, doi. 10.1002/emmm.201000112
By:
- Ermakova, Olga;
- Piszczek, Lukasz;
- Luciani, Luisa;
- Cavalli, Florence M. G.;
- Ferreira, Tiago;
- Farley, Dominika;
- Rizzo, Stefania;
- Paolicelli, Rosa Chiara;
- Al-Banchaabouchi, Mumna;
- Nerlov, Claus;
- Moriggl, Richard;
- Luscombe, Nicholas M.;
- Gross, Cornelius
Publication type:
Article
CD155 is a putative therapeutic target in medulloblastoma.
Published in:
Clinical & Translational Oncology, 2023, v. 25, n. 3, p. 696, doi. 10.1007/s12094-022-02975-9
By:
- Li, Sean;
- McLendon, Roger;
- Sankey, Eric;
- Kornahrens, Reb;
- Lyne, Anne-Marie;
- Cavalli, Florence Marie Géraldine;
- McKay, Zachary;
- Herndon II, James Emmett;
- Remke, Marc;
- Picard, Daniel;
- Gromeier, Matthias;
- Brown, Michael;
- Thompson, Eric Michael
Publication type:
Article
Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.64090
By:
- Guilhamon, Paul;
- Chesnelong, Charles;
- Kushida, Michelle M.;
- Nikolic, Ana;
- Singhal, Divya;
- MacLeod, Graham;
- Madani Tonekaboni, Seyed Ali;
- Cavalli, Florence M. G.;
- Arlidge, Christopher;
- Rajakulendran, Nishani;
- Rastegar, Naghmeh;
- Xiaoguang Hao;
- Hassam, Rozina;
- Smith, Laura J.;
- Whetstone, Heather;
- Coutinho, Fiona J.;
- Nadorp, Bettina;
- Ellestad, Katrina I.;
- Luchman, H. Artee;
- Ai-wen Chan, Jennifer
Publication type:
Article
The transcriptional landscape of Shh medulloblastoma.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21883-0
By:
- Skowron, Patryk;
- Farooq, Hamza;
- Cavalli, Florence M. G.;
- Morrissy, A. Sorana;
- Ly, Michelle;
- Hendrikse, Liam D.;
- Wang, Evan Y.;
- Djambazian, Haig;
- Zhu, Helen;
- Mungall, Karen L.;
- Trinh, Quang M.;
- Zheng, Tina;
- Dai, Shizhong;
- Stucklin, Ana S. Guerreiro;
- Vladoiu, Maria C.;
- Fong, Vernon;
- Holgado, Borja L.;
- Nor, Carolina;
- Wu, Xiaochong;
- Abd-Rabbo, Diala
Publication type:
Article
Integrated genomics elucidates relative spatial homogeneity of embryonal brain tumors.
Published in:
2015
By:
- Remke, Marc;
- Cavalli, Florence;
- Morrissy, A;
- Ramaswamy, Vijay;
- Jones, David;
- Packer, Roger;
- Bouffet, Eric;
- Bader, Gary;
- Borkhardt, Arndt;
- Pfister, Stefan;
- Jabado, Nada;
- Marra, Marco;
- Taylor, Michael
Publication type:
Abstract
Integrated analysis of proteome, phosphotyrosine-proteome, tyrosine-kinome, and tyrosine-phosphatome in acute myeloid leukemia.
Published in:
Proteomics, 2017, v. 17, n. 6, p. n/a, doi. 10.1002/pmic.201600361
By:
- Tong, Jiefei;
- Helmy, Mohamed;
- Cavalli, Florence M. G.;
- Jin, Lily;
- St‐Germain, Jonathan;
- Karisch, Robert;
- Taylor, Paul;
- Minden, Mark D.;
- Taylor, Michael D.;
- Neel, Benjamin G.;
- Bader, Gary D.;
- Moran, Michael F.
Publication type:
Article
MEDU-40. MATCHING OF SINGLE CELL TRANSCRIPTOMICS FROM CEREBELLAR DEVELOPMENT IDENTIFIES PUTATIVE SUBGROUP SPECIFIC CELLS OF ORIGIN FOR MEDULLOBLASTOMA.
Published in:
Neuro-Oncology, 2019, v. 21, p. ii111, doi. 10.1093/neuonc/noz036.198
By:
- El-Hamamy, Ibrahim;
- Vladoiu, Maria;
- Donovan, Laura;
- Farooq, Hamza;
- Holgado, Borja;
- Ramaswamy, Vijay;
- Cavalli, Florence;
- Luu, Betty;
- Chan, Jennifer;
- Kleinman, Claudia;
- Joyner, Alexandra;
- Jabado, Nada;
- Stein, Lincoln;
- Taylor, Michael
Publication type:
Article
IMMU-03. TUMOR NECROSIS FACTOR OVERCOMES IMMUNE EVASION IN P53-MUTANT MEDULLOBLASTOMA.
Published in:
Neuro-Oncology, 2019, v. 21, p. ii93, doi. 10.1093/neuonc/noz036.124
By:
- Garancher, Alexandra;
- Suzuki, Hiromichi;
- Haricharan, Svasti;
- Masihi, Meher Beigi;
- Rusert, Jessica M;
- Norris, Paula S;
- Carrette, Florent;
- Romero, Megan M;
- Morrissy, Sorana A;
- Skowron, Patryk;
- Cavalli, Florence M.G.;
- Farooq, Hamza;
- Ramaswamy, Vijay;
- Jones, Steven J.M.;
- Moore, Richard A;
- Mungall, Andrew J;
- Ma, Yussanne;
- Thiessen, Nina;
- Li, Yisu;
- Morcavallo, Alaide
Publication type:
Article
PDTM-21. MATCHING OF SINGLE CELL TRANSCRIPTOMICS FROM CEREBELLAR DEVELOPMENT IDENTIFIES PUTATIVE SUBGROUP SPECIFIC CELLS OF ORIGIN FOR MEDULLOBLASTOMA.
Published in:
Neuro-Oncology, 2018, v. 20, p. vi208, doi. 10.1093/neuonc/noy148.863
By:
- El-Hamamy, Ibrahim;
- Vladoiu, Maria;
- Donovan, Laura;
- Cavalli, Florence;
- Ramaswamy, Vijay;
- Farooq, Hamza;
- Lopez, Borja;
- Kleinman, Claudia;
- Chan, Jennifer;
- Singh, Sheila
Publication type:
Article
SpeCond: a method to detect condition-specific gene expression.
Published in:
Genome Biology, 2011, v. 12, n. 10, p. 1, doi. 10.1186/gb-2011-12-10-r101
By:
- Cavalli, Florence M. G.;
- Bourgon, Richard;
- Huber, Wolfgang;
- Vaquerizas, Juan M.;
- Luscombe, Nicholas M.
Publication type:
Article
Subgroup-specific prognostic signaling and metabolic pathways in pediatric medulloblastoma.
Published in:
2019
By:
- Park, Ae Kyung;
- Lee, Ji Yeoun;
- Cheong, Heesun;
- Ramaswamy, Vijay;
- Park, Sung-Hye;
- Kool, Marcel;
- Phi, Ji Hoon;
- Choi, Seung Ah;
- Cavalli, Florence;
- Taylor, Michael D.;
- Kim, Seung-Ki
Publication type:
journal article
ABL1 and ABL2 promote medulloblastoma leptomeningeal dissemination.
Published in:
Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad095
By:
- Jones, Jill K;
- Zhang, Hengshan;
- Lyne, Anne-Marie;
- Cavalli, Florence M G;
- Hassen, Wafa E;
- Stevenson, Kevin;
- Kornahrens, Reb;
- Yang, Yuanfan;
- Li, Sean;
- Dell, Samuel;
- Reitman, Zachary J;
- Herndon, James E;
- Hoj, Jacob;
- Pendergast, Ann Marie;
- Thompson, Eric M
Publication type:
Article
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes.
Published in:
Acta Neuropathologica, 2019, v. 138, n. 2, p. 309, doi. 10.1007/s00401-019-02020-0
By:
- Sharma, Tanvi;
- Schwalbe, Edward C.;
- Williamson, Daniel;
- Sill, Martin;
- Hovestadt, Volker;
- Mynarek, Martin;
- Rutkowski, Stefan;
- Robinson, Giles W.;
- Gajjar, Amar;
- Cavalli, Florence;
- Ramaswamy, Vijay;
- Taylor, Michael D.;
- Lindsey, Janet C.;
- Hill, Rebecca M.;
- Jäger, Natalie;
- Korshunov, Andrey;
- Hicks, Debbie;
- Bailey, Simon;
- Kool, Marcel;
- Chavez, Lukas
Publication type:
Article
Heterogeneity within the PF-EPN-B ependymoma subgroup.
Published in:
Acta Neuropathologica, 2018, v. 136, n. 2, p. 227, doi. 10.1007/s00401-018-1888-x
By:
- Cavalli, Florence M. G.;
- Hübner, Jens-Martin;
- Sharma, Tanvi;
- Luu, Betty;
- Sill, Martin;
- Zapotocky, Michal;
- Mack, Stephen C.;
- Witt, Hendrik;
- Lin, Tong;
- Shih, David J. H.;
- Ho, Ben;
- Santi, Mariarita;
- Emery, Lyndsey;
- Hukin, Juliette;
- Dunham, Christopher;
- McLendon, Roger E.;
- Lipp, Eric S.;
- Gururangan, Sridharan;
- Grossbach, Andrew;
- French, Pim
Publication type:
Article
Medulloblastoma subgroups remain stable across primary and metastatic compartments.
Published in:
Acta Neuropathologica, 2015, v. 129, n. 3, p. 449, doi. 10.1007/s00401-015-1389-0
By:
- Wang, Xin;
- Dubuc, Adrian;
- Ramaswamy, Vijay;
- Mack, Stephen;
- Gendoo, Deena;
- Remke, Marc;
- Wu, Xiaochong;
- Garzia, Livia;
- Luu, Betty;
- Cavalli, Florence;
- Peacock, John;
- López, Borja;
- Skowron, Patryk;
- Zagzag, David;
- Lyden, David;
- Hoffman, Caitlin;
- Cho, Yoon-Jae;
- Eberhart, Charles;
- MacDonald, Tobey;
- Li, Xiao-Nan
Publication type:
Article
<i>TERT</i> promoter mutations are highly recurrent in SHH subgroup medulloblastoma.
Published in:
Acta Neuropathologica, 2013, v. 126, n. 6, p. 917, doi. 10.1007/s00401-013-1198-2
By:
- Remke, Marc;
- Ramaswamy, Vijay;
- Peacock, John;
- Shih, David J. H.;
- Koelsche, Christian;
- Northcott, Paul A.;
- Hill, Nadia;
- Cavalli, Florence M. G.;
- Kool, Marcel;
- Wang, Xin;
- Mack, Stephen C.;
- Barszczyk, Mark;
- Morrissy, A. Sorana;
- Wu, Xiaochong;
- Agnihotri, Sameer;
- Luu, Betty;
- Jones, David T. W.;
- Garzia, Livia;
- Dubuc, Adrian M.;
- Zhukova, Nataliya
Publication type:
Article
Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays.
Published in:
2013
By:
- Hovestadt, Volker;
- Remke, Marc;
- Kool, Marcel;
- Pietsch, Torsten;
- Northcott, Paul;
- Fischer, Roger;
- Cavalli, Florence;
- Ramaswamy, Vijay;
- Zapatka, Marc;
- Reifenberger, Guido;
- Rutkowski, Stefan;
- Schick, Matthias;
- Bewerunge-Hudler, Melanie;
- Korshunov, Andrey;
- Lichter, Peter;
- Taylor, Michael;
- Pfister, Stefan;
- Jones, David
Publication type:
Letter
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma.
Published in:
Nature, 2014, v. 511, n. 7510, p. 428, doi. 10.1038/nature13379
By:
- Northcott, Paul A.;
- Lee, Catherine;
- Zichner, Thomas;
- Stütz, Adrian M.;
- Erkek, Serap;
- Kawauchi, Daisuke;
- Shih, David J. H.;
- Hovestadt, Volker;
- Zapatka, Marc;
- Sturm, Dominik;
- Jones, David T. W.;
- Kool, Marcel;
- Remke, Marc;
- Cavalli, Florence M. G.;
- Zuyderduyn, Scott;
- Bader, Gary D.;
- VandenBerg, Scott;
- Esparza, Lourdes Adriana;
- Ryzhova, Marina;
- Wang, Wei
Publication type:
Article
PRMT5 inhibition disrupts splicing and stemness in glioblastoma.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21204-5
By:
- Sachamitr, Patty;
- Ho, Jolene C.;
- Ciamponi, Felipe E.;
- Ba-Alawi, Wail;
- Coutinho, Fiona J.;
- Guilhamon, Paul;
- Kushida, Michelle M.;
- Cavalli, Florence M. G.;
- Lee, Lilian;
- Rastegar, Naghmeh;
- Vu, Victoria;
- Sánchez-Osuna, María;
- Coulombe-Huntington, Jasmin;
- Kanshin, Evgeny;
- Whetstone, Heather;
- Durand, Mathieu;
- Thibault, Philippe;
- Hart, Kirsten;
- Mangos, Maria;
- Veyhl, Joseph
Publication type:
Article

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