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- Title
Inflammation, Insulin Resistance, and DiabetesMendelian Randomization Using CRP Haplotypes Points Upstream.
- Authors
Brunner, Eric J.; Kivimki, Mika; Witte, Daniel R.; Lawlor$2, Debbie A.; Smith, George Davey; Cooper, Jackie A.; Miller, Michelle; Lowe, Gordon D. O.; Rumley, Ann; Casas, Juan P.; Shah, Tina; Humphries, Steve E.; Hingorani, Aroon D.; Marmot, Michael G.; Timpson, Nicholas J.; Kumari, Meena
- Abstract
Using a Mendelian randomization approach, Eric Brunner and colleagues show that the associations between serum C-reactive protein and insulin resistance, glycemia, and diabetes are likely to be noncausal.
- Subjects
C-reactive protein; TYPE 2 diabetes; INSULIN resistance; HYPOGLYCEMIC agents; DIABETES complications; SERUM
- Publication
PLoS Medicine, 2008, Vol 5, Issue 8, pe155
- ISSN
1549-1277
- Publication type
Article
- DOI
10.1371/journal.pmed.0050155