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- Title
Depression Among HIV-infected Patients in Korea: Assessment of Clinical Significance and Risk Factors.
- Authors
Joon Young Song; Jin Soo Lee; Yu Bin Seo; In Seon Kim; Ji Youn Noh; Ji Hyeon Baek; Hee Jin Cheong; Woo Joo Kim
- Abstract
Background: With prolonged life expectancies, mental illness has emerged as a disabling disorder among people with HIV. Materials and Methods: This study was conducted to assess the prevalence of depression and its risk factors among Korean patients with HIV infections. Eighty-two HIV-infected patients completed structured questionnaires including the Beck Depression Inventory and the State-Trait Anxiety Inventory. Subjects with depression were compared to those without depression in terms of demographics, comorbidities, CD4 T-cell count, RNA copy numbers, highly active antiretroviral therapy (HAART) regimens, and adherence. Results: The estimated depression rate was 21% (17 of 82 subjects). Comorbidities (47% vs. 20%, P = 0.01) and unemployment (65% vs. 31%, P = 0.02) were risk factors for depression. Depressive patients were more likely to be anxious (71% vs. 29%, P < 0.01), to frequently miss clinical appointments each year (P = 0.04), and to have higher cumulative time lost to follow-up per month (P <0.01) compared to non-depressive patients. Only three depressive patients were referred to neuropsychologists. Conclusions: More than 20% of the Korean HIV patients in this study suffered from depression associated with poor adherence. Considering the low level of recognition of depression by clinicians, risk factor-based active assessment is recommended to manage depression properly in HIV-infected patients.
- Subjects
PSYCHOLOGY of HIV-positive persons; DIAGNOSIS of mental depression; BECK Depression Inventory; ANXIETY; HIGHLY active antiretroviral therapy
- Publication
Infection & Chemotherapy, 2013, Vol 45, Issue 2, p211
- ISSN
2093-2340
- Publication type
Article
- DOI
10.3947/ic.2013.45.2.211