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- Title
Interaction effects between angiotensin‐converting enzyme inhibitors or angiotensin receptor blockers and steroid or antiviral therapies in COVID‐19: A population‐based study.
- Authors
Zhou, Jiandong; Tse, Gary; Lee, Sharen; Liu, Tong; Cao, Zhidong; Zeng, Daniel Dajun; Leung, Keith Sai Kit; Wai, Abraham Ka Chung; Wong, Ian Chi Kei; Cheung, Bernard Man Yung; Zhang, Qingpeng
- Abstract
Therefore, ACEI use was protective of the severe disease outcome in COVID-19 patients receiving steroid therapy. Interaction effects between angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and steroid or antiviral therapies in COVID-19: A population-based study Interaction effects between ACEIs, ARBs, and individual drugs in these classes with antiviral therapies or steroids were assessed in the unmatched cohort (Table 2). A noteworthy point is that the renin-angiotensin-aldosterone system may interact with the Kinin-Kallikrein system and coagulation cascade.11 Therefore, at the very least, interactions aside, prevention of thromboembolic phenomena may improve outcomes in COVID-19 patients.
- Subjects
ANGIOTENSIN receptors; COVID-19 treatment; ANGIOTENSIN-receptor blockers; STEROID drugs; ACE inhibitors; STEROID receptors; TRANSIENT ischemic attack; COVID-19
- Publication
Journal of Medical Virology, 2021, Vol 93, Issue 5, p2635
- ISSN
0146-6615
- Publication type
Article
- DOI
10.1002/jmv.26904