We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Micro-organisms and risk factors associated with prosthetic joint infection following primary total knee replacement-our experience in Pakistan.
- Authors
Iqbal, Faizan; Shafiq, Bilal; Zamir, Mehroz; Noor, Shahid; Memon, Noman; Memon, Naveed; Dina, Twahir Kalekhan
- Abstract
<bold>Purpose: </bold>To identify potential risk factors and micro-organisms associated with prosthetic joint infection following primary total knee replacement surgery.<bold>Hypothesis Of Study: </bold>Our hypothesis is that body mass index (BMI), operative time, type of surgery, and order of surgery especially in bilateral simultaneous cases have a major impact on prosthetic joint infection (PJI).<bold>Methodology: </bold>We identified 4269 patients who underwent for primary knee replacement surgery between 2008 and 2018. We recorded patient demographics, comorbidities, order of surgery, type of surgery, causative micro-organism, and their antibiotic susceptibility. Multivariable logistic regression analysis was built to identify risk factors that are associated with prosthetic joint infection following primary total knee replacement.<bold>Results: </bold>Forty-eight patients developed prosthetic joint infection. The factors that are found to be associated with prosthetic joint infection are BMI, operative time, type of surgery, order of surgery, diabetes, and rheumatoid arthritis. Methicillin-resistant Staphylococcus aureus (MRSA) was the major underlying pathogen seen in majority of cases.<bold>Conclusion: </bold>Despite low incidence of prosthetic joint infection following primary total knee replacement, there are patients at higher risk that would benefit by addressing modifying risk factors significantly associated with prosthetic joint infection.
- Subjects
PAKISTAN; JOINT infections; TOTAL knee replacement; ARTIFICIAL joints; INFECTION; KNEE surgery; METHICILLIN-resistant staphylococcus aureus; TOTAL ankle replacement; DO-not-resuscitate orders
- Publication
International Orthopaedics, 2020, Vol 44, Issue 2, p283
- ISSN
0341-2695
- Publication type
journal article
- DOI
10.1007/s00264-019-04472-1