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- Title
Hyperuricaemia, Xanthine Oxidoreductase and Ribosome-Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research.
- Authors
Bolognesi, Andrea; Bortolotti, Massimo; Battelli, Maria Giulia; Polito, Letizia
- Abstract
The enzymes called ribosome-inactivating proteins (RIPs) that are able to depurinate nucleic acids and arrest vital cellular functions, including protein synthesis, are still a frontline research field, mostly because of their promising medical applications. The contributions of Stirpe to the development of these studies has been one of the most relevant. After a short biographical introduction, an overview is offered of the main results obtained by his investigations during last 55 years on his main research lines: hyperuricaemia, xanthine oxidoreductase and RIPs.
- Subjects
RIBOSOME-inactivating proteins; PROTEIN synthesis; PLANT proteins; HYPERURICEMIA; XANTHINE oxidase; XANTHINURIA; THERAPEUTICS
- Publication
Molecules, 2017, Vol 22, Issue 2, p206
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules22020206