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- Title
Effect of Different Psychoactive Substances on Hematological Parameters of Dependents in Türkiye.
- Authors
Şanlı, Dilek Beker; Bilici, Rabia
- Abstract
Background: In this study we aimed to define the effects of psychoactive substances on hematological parameters. Materials and Methods: Three hundred-nineteen dependents, 82 control subjects were involved in this study. Diagnostic and statistical manual of mental disorders-IV criteria is used to determine patient group. We obtained the complete blood count and toxicology parameters in all cases and controls. Study participants with additional chronic diseases are not included. Results: Changes in hematological parameters according to the urine toxicology results were evaluated for statistical significance. There were statistically significant differences in red blood cell (RBC), mean corpuscular value (MCV), hemoglobin (HGB), hematocrit (HCT), medians between dependent group and control group (p<0.05). We found a statistically significant difference in RBC, MCV, HGB and HCT levels between the opium dependent group and control group (p<0.05). The difference was also significant between HGB, neutrophil (NEU)%, MCH, RDW levels of cannabinoid dependent group compared to control group (p<0.05). We found a statistically significant difference in monocyte%, lymphocyte%, NEU%, eosinophil% levels between benzodiazepine group and control group (p<0.05). Whereas in ethyl glucuronide group significant difference observed only in neutrophile count (p<0.05). Conclusion: Monitoring hematological parameters in psychoactive substance dependents can be used to confirm need for special treatment programs.
- Subjects
PSYCHIATRIC drugs; HEMATOLOGIC agents; HEMATOCRIT; ETHYL glucuronide; BENZODIAZEPINES
- Publication
Hamidiye Medical Journal, 2022, Vol 3, Issue 3, p191
- ISSN
2718-0956
- Publication type
Article
- DOI
10.4274/hamidiyemedj.galenos.2022.29290