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- Title
THE RELATIONSHIP OF SERUM MELATONIN LEVELS WITH INFANTILE COLIC.
- Authors
CENGIZ, Nihat; KUREKC, Emin; OZENC, Salim; BALAMTEK, Necati
- Abstract
OBJECTIVE: The serotonin concentration peaks at night which causes intestinal cramps. Both serotonin and melatonin have circadian rhythms and they peak at night. While there are only serotonin circadian rhythms during birth, the melatonin circadian rhythms begin after 3rd month. It is argued that serotonin is high and melatonin is low for the infants who have colic, yet there are no studies proving this argument. MATERIAL AND METHOD: The study population is chosen with a developed random sampling method among 50 infants who have infantile colic and 66 infant as healthy control group. RESULTS: The melatonin levels of the blood samples are taken from both groups at 09.00 am and also from 20 infants with infantile colic blood samples were taken 09.00 pm. The melatonin level of the infants who have infantile colic is found lower than the control group (P: 0.014). The evening melatonin levels in babies with infantile colic were significantly higher compared to morning levels (P < 0.001). CONCLUSION: Serum melatonin levels of studying group have been found lower and also as statistically significant. The results of our study support the hypothesis that the decrease of melatonin causes infantile colic
- Publication
Balkan Military Medical Review, 2014, Vol 17, p17
- ISSN
1107-6275
- Publication type
Article