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- Title
The association of serum uric acid/albumin ratio with the development of coronary collateral circulation in patients with chronic total occluded coronary arteries.
- Authors
Şaylık, Faysal; Çınar, Tufan; Sarıkaya, Remzi; Akbulut, Tayyar; Selçuk, Murat; Özbek, Emrah; Tanboğa, İbrahim Halil
- Abstract
Introduction: Coronary collateral circulation (CCC) develops in chronic total occluded (CTO) vessels and protects the myocardium against ischemia in addition to the improvement of cardiac functions. Poor CCC is related to adverse cardiac events as well as poor prognosis. Serum uric acid/albumin ratio (UAR) has emerged as a novel marker associated with poor cardiovascular outcomes. We aimed to investigate whether there was an association between UAR and poor CCC in CTO patients. Methods: This study was comprised of 212 patients with CTO (92 with poor CCC and 120 with good CCC). All patients were graded based on Rentrop scores to poor CCC (Rentrop scores 0 and 1) and good CCC (Rentrop scores 2 and 3). Results: Poor CCC patients had higher frequencies of diabetes mellitus, triglyceride levels, Syntax and Gensini scores, uric acid, and UAR and lower lymphocyte, high-density lipoprotein cholesterol, and ejection fraction when compared to good CCC patients. UAR was an independent predictor of poor CCC in CTO patients. Furthermore, UAR had a better discriminative ability for patients with poor CCC from good CCC compared to serum uric acid and albumin. Conclusion: Based on the results of the study, the UAR could be used to detect poor CCC in CTO patients.
- Subjects
ALBUMINS; BIOMARKERS; COLLATERAL circulation; CHRONIC diseases; URIC acid; CORONARY occlusion; CORONARY arteries
- Publication
Journal of Cardiovascular & Thoracic Research, 2023, Vol 15, Issue 1, p14
- ISSN
2008-5117
- Publication type
Article
- DOI
10.34172/jcvtr.2023.31627