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- Title
Impact of early surgery after aneurysmal subarachnoid haemorrhage.
- Authors
van der Jagt, M.; Hasan, D.; Dippel, D. W. J.; van Dijk, E. J.; Avezaat, C. J. J.; Koudstaal, P. J.
- Abstract
Objectives – To investigate the effect of early aneurysm surgery (<72 h) on outcome in patients with subarachnoid haemorrhage (SAH). Materials and methods – We studied two consecutive series of patients with aneurysmal SAH [postponed surgery (PS) cohort, n = 118, 1989–1992: surgery was planned on day 12 and early surgery (ES) cohort, n = 85, 1996–1998: ES was performed only in patients with Glasgow Coma Scale (GCS) >13]. We used multivariable logistic regression analysis to assess outcome at 3 months. Results – Favourable outcome (Glasgow Outcome Scale 4 or 5) was similar in both cohorts. Cerebral ischemia occurred significantly more often in the ES cohort. The occurrence of rebleeds was similar in both cohorts. External cerebrospinal fluid (CSF) drainage was performed more often in the ES cohort (51% vs 19%). Patients with cisternal sum score (CSS) of subarachnoid blood <15 on admission [adjusted odds ratio (OR) for favourable outcome: 6.4, 95% confidence interval (CI) 1.0–39.8] and patients with both CSS <15 and GCS > 12 on admission benefited from the strategy including ES (OR 10.5, 95% CI 1.1–99.4). Conclusions – Our results support the widely adopted practice of ES in good-grade SAH patients.
- Subjects
CEREBROSPINAL fluid; REGRESSION analysis; ISCHEMIA; STATISTICAL hypothesis testing; AGRICULTURAL engineering; CONFIDENCE intervals; CEREBRAL ischemia; BLOOD circulation disorders; HYDRAULIC engineering; SPINAL cord; LOGISTIC regression analysis
- Publication
Acta Neurologica Scandinavica, 2009, Vol 119, Issue 2, p100
- ISSN
0001-6314
- Publication type
Article
- DOI
10.1111/j.1600-0404.2008.01064.x