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- Title
Infliximab-Induced Lupus Causing Pericarditis: a Case Report and Review of the Literature.
- Authors
Thiriveedi, Mrudula; Steuber, Taylor D.; Hasan, Mohamed; Baggett, Alan
- Abstract
A diagnosis of drug-induced lupus erythematosus (DILE) causing pericarditis with pericardial effusion due to infliximab was made in view of the temporal association of symptoms and positive clinical and serological evidence. Previous Presentation The abstract of this manuscript was presented as a poster presentation at the 2019 Alabama/Mississippi ACP Scientific Meeting, held at The University of Mississippi Medical Center in Jackson, MS. Her past medical history was significant for fistulizing Crohn's disease (CD) diagnosed in 2011, status post hemicolectomy. Vedolizumab does not act on the TNF- pathway, has not been associated with DILE, and possesses a favorable safety profile overall.[7], [20], [21] Furthermore, vedolizumab has been used successfully in a patient who experienced pericarditis due to infliximab-induced DILE without recurrence.[13] For this reason, vedolizumab has been considered for our patient although she has not started as she is currently maintained on low-dose corticosteroids which she is tolerating well.
- Subjects
PERICARDITIS; SYSTEMIC lupus erythematosus; MEDICAL personnel; LITERATURE reviews; IMMUNOMODULATORS
- Publication
JGIM: Journal of General Internal Medicine, 2021, Vol 36, Issue 7, p2134
- ISSN
0884-8734
- Publication type
Article
- DOI
10.1007/s11606-021-06781-x