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- Title
Germatranyl Substituted Mono- and Di-organotin(IV) Carboxylates: Synthesis, Characterization and Biological Activities.
- Authors
Salma, U.; Mazhar, M.; Imtiaz-ud-Din; Ali, S.
- Abstract
Seven new germatranes having the general formula [R1GeCH(R2)CH2COO]4-nSnRn3 where R1 = N(CH2CH2O)3 , R2 = CH3, C6H5, p-CH3C6H4, p-CH3OC6H9, p-FC6H4, R3= C6H5,CH2C6H5, n = 1 or 2, have been synthesized by the reaction of mono-, or di-organotin halide with germatranyl propionic acid in the presence of triethylamine and were characterized by elemental analysis, multinuclear (1H, 13C, 119Sn) NMR, 119mSn Mossbauer,IR and mass spectrometry. Anti-leishmanial and enzyme inhibition bioassay techniques were employed to evaluate their activity and found promising results.
- Publication
Main Group Metal Chemistry, 2007, Vol 30, Issue 5, p259
- ISSN
0792-1241
- Publication type
Article