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- Title
Post-thrombotic syndrome and chronic thromboembolic pulmonary hypertension: diagnosis and management.
- Authors
Tsiamita, Olga; White, Katie
- Abstract
Post-thrombotic syndrome and chronic thromboembolic pulmonary hypertension are two distinct clinical syndromes associated with adverse patient outcomes following a venous thromboembolism. Clinical manifestations of post-thrombotic syndrome include persistent pain, swelling and ultimately venous ulceration following a deep venous thrombosis. Patients experiencing chronic thromboembolic pulmonary hypertension may have symptoms ranging from exertional dyspnoea to overt right heart failure. From a physician's perspective, the most effective preventative strategy is good quality anticoagulation for prophylaxis of primary and secondary venous thromboembolism. The treatment of post-thrombotic syndrome mainly involves lifestyle modifications alongside the use of elastic compression stockings while patients with chronic thromboembolic pulmonary hypertension should be offered targeted surgical and medical treatment options available at expert centres. Further research is warranted for both conditions to determine the role of direct oral anticoagulants when used with a preventive or therapeutic intent.
- Subjects
PULMONARY hypertension diagnosis; PULMONARY hypertension treatment; VEINS; PULMONARY embolism; PAIN; ANTICOAGULANTS; COMPRESSION bandages; VENOUS thrombosis; DYSPNEA; THROMBOEMBOLISM; HEALTH behavior; LEG ulcers; POSTTHROMBOTIC syndrome; BEHAVIOR modification; EDEMA; HEART failure; DISEASE complications
- Publication
British Journal of Hospital Medicine (17508460), 2023, Vol 84, Issue 8, p1
- ISSN
1750-8460
- Publication type
Article
- DOI
10.12968/hmed.2023.0114