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Enhancing sepsis biomarker development: key considerations from public and private perspectives.
Published in:
Critical Care, 2024, v. 28, n. 1, p. 1, doi. 10.1186/s13054-024-05032-9
By:
- Llitjos, Jean-Francois;
- Carrol, Enitan D.;
- Osuchowski, Marcin F.;
- Bonneville, Marc;
- Scicluna, Brendon P.;
- Payen, Didier;
- Randolph, Adrienne G.;
- Witte, Stephan;
- Rodriguez-Manzano, Jesus;
- François, Bruno
Publication type:
Article
Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice.
Published in:
Journal of Pathology, 2020, v. 250, n. 1, p. 95, doi. 10.1002/path.5354
By:
- Ding, Chao;
- Scicluna, Brendon P;
- Stroo, Ingrid;
- Yang, Jack;
- Roelofs, Joris JTH;
- Boer, Onno J;
- Vos, Alex F;
- Nürnberg, Peter;
- Revenko, Alexey S;
- Crosby, Jeff;
- Veer, Cornelis;
- Poll, Tom
Publication type:
Article
Genome-wide analyses in Lyme borreliosis: identification of a genetic variant associated with disease susceptibility and its immunological implications.
Published in:
BMC Infectious Diseases, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12879-024-09217-z
By:
- Vrijmoeth, Hedwig D.;
- Ursinus, Jeanine;
- Botey-Bataller, Javier;
- Kuijpers, Yunus;
- Chu, Xiaojing;
- van de Schoor, Freek R.;
- Scicluna, Brendon P.;
- Xu, Cheng-Jian;
- Netea, Mihai G.;
- Kullberg, Bart Jan;
- van den Wijngaard, Cees C.;
- Li, Yang;
- Hovius, Joppe W.;
- Joosten, Leo A. B.
Publication type:
Article
The leukocyte non-coding RNA landscape in critically ill patients with sepsis.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.58597
By:
- Scicluna, Brendon P.;
- Uhel, Fabrice;
- van Vught, Lonneke A.;
- Wiewel, Maryse A.;
- Hoogendijk, Arie J.;
- Baessman, Ingelore;
- Franitza, Marek;
- Nürnberg, Peter;
- Horn, Janneke;
- Cremer, Olaf L.;
- Bonten, Marc J.;
- Schultz, Marcus J.;
- van der Poll, Tom
Publication type:
Article
Human Adipose‐Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae.
Published in:
Stem Cells Translational Medicine, 2019, v. 8, n. 8, p. 785, doi. 10.1002/sctm.18-0260
By:
- Perlee, Desiree;
- Vos, Alex F.;
- Scicluna, Brendon P.;
- Mancheño, Pablo;
- Rosa, Olga;
- Dalemans, Wilfried;
- Nürnberg, Peter;
- Lombardo, Eleuterio;
- Poll, Tom
Publication type:
Article
HIVEP1 Is a Negative Regulator of NF-κB That Inhibits Systemic Inflammation in Sepsis.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.744358
By:
- Matsumoto, Hisatake;
- Scicluna, Brendon P.;
- Jim, Kin Ki;
- Falahi, Fahimeh;
- Qin, Wanhai;
- Gürkan, Berke;
- Malmström, Erik;
- Meijer, Mariska T.;
- Butler, Joe M.;
- Khan, Hina N.;
- Takagi, Tsuyoshi;
- Ishii, Shunsuke;
- Schultz, Marcus J.;
- van de Beek, Diederik;
- de Vos, Alex F.;
- van 't Veer, Cornelis;
- van der Poll, Tom
Publication type:
Article
The Long Non-Coding Antisense RNA JHDM1D-AS1 Regulates Inflammatory Responses in Human Monocytes.
Published in:
Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.934313
By:
- Malmström, Erik;
- Khan, Hina N.;
- van 't Veer, Cornelis;
- Stunnenberg, Melissa;
- Meijer, Mariska T.;
- Matsumoto, Hisatake;
- Otto, Natasja A.;
- Geijtenbeek, Teunis B. H.;
- de Vos, Alex F.;
- van der Poll, Tom;
- Scicluna, Brendon P.
Publication type:
Article
An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration.
Published in:
Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00948-1
By:
- Brands, Xanthe;
- Haak, Bastiaan W.;
- Klarenbeek, Augustijn M.;
- Butler, Joe;
- Uhel, Fabrice;
- Qin, Wanhai;
- Otto, Natasja A.;
- Jakobs, Marja E.;
- Faber, Daniël R.;
- Lutter, René;
- Wiersinga, W. Joost;
- van der Poll, Tom;
- Scicluna, Brendon P.
Publication type:
Article
Ferritin heavy chain supports stability and function of the regulatory T cell lineage.
Published in:
EMBO Journal, 2024, v. 43, n. 8, p. 1445, doi. 10.1038/s44318-024-00064-x
By:
- Wu, Qian;
- Carlos, Ana Rita;
- Braza, Faouzi;
- Bergman, Marie-Louise;
- Kitoko, Jamil Z;
- Bastos-Amador, Patricia;
- Cuadrado, Eloy;
- Martins, Rui;
- Oliveira, Bruna Sabino;
- Martins, Vera C;
- Scicluna, Brendon P;
- Landry, Jonathan JM;
- Jung, Ferris E;
- Ademolue, Temitope W;
- Peitzsch, Mirko;
- Almeida-Santos, Jose;
- Thompson, Jessica;
- Cardoso, Silvia;
- Ventura, Pedro;
- Slot, Manon
Publication type:
Article
Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction.
Published in:
Nature Genetics, 2010, v. 42, n. 8, p. 688, doi. 10.1038/ng.623
By:
- Bezzina, Connie R.;
- Pazoki, Raha;
- Bardai, Abdennasser;
- Marsman, Roos F.;
- de Jong, Jonas S. S. G.;
- Blom, Marieke T.;
- Scicluna, Brendon P.;
- Jukema, J. Wouter;
- Bindraban, Navin R.;
- Lichtner, Peter;
- Pfeufer, Arne;
- Bishopric, Nanette H.;
- Roden, Dan M.;
- Meitinger, Thomas;
- Chugh, Sumeet S.;
- Myerburg, Robert J.;
- Jouven, Xavier;
- Kääb, Stefan;
- Dekker, Lukas R. C.;
- Tan, Hanno L.
Publication type:
Article
The gut microbiota as a modulator of innate immunity during melioidosis.
Published in:
PLoS Neglected Tropical Diseases, 2017, v. 11, n. 4, p. 1, doi. 10.1371/journal.pntd.0005548
By:
- Lankelma, Jacqueline M.;
- Birnie, Emma;
- Weehuizen, Tassili A. F.;
- Scicluna, Brendon P.;
- Belzer, Clara;
- Houtkooper, Riekelt H.;
- Roelofs, Joris J. T. H.;
- de Vos, Alex F.;
- van der Poll, Tom;
- Budding, Andries E.;
- Wiersinga, W. Joost
Publication type:
Article
Role of Tumor Necrosis Factor-α in the Human Systemic Endotoxin-Induced Transcriptome.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079051
By:
- Scicluna, Brendon P.;
- van 't Veer, Cornelis;
- Nieuwdorp, Max;
- Felsmann, Karen;
- Wlotzka, Britta;
- Stroes, Erik S. G.;
- van der Poll, Tom
Publication type:
Article
Biological Subphenotypes of Acute Respiratory Distress Syndrome Show Prognostic Enrichment in Mechanically Ventilated Patients without Acute Respiratory Distress Syndrome.
Published in:
2021
By:
- Heijnen, Nanon F. L.;
- Hagens, Laura A.;
- Smit, Marry R.;
- Cremer, Olaf L.;
- Ong, David S. Y.;
- van der Poll, Tom;
- van Vught, Lonneke A.;
- Scicluna, Brendon P.;
- Schnabel, Ronny M.;
- van der Horst, Iwan C. C.;
- Schultz, Marcus J.;
- Bergmans, Dennis C. J. J.;
- Bos, Lieuwe D. J.
Publication type:
journal article
Understanding Heterogeneity in Biologic Phenotypes of Acute Respiratory Distress Syndrome by Leukocyte Expression Profiles.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2019, v. 200, n. 1, p. 42, doi. 10.1164/rccm.201809-1808OC
By:
- Bos, Lieuwe D. J.;
- Scicluna, Brendon P.;
- Ong, David S. Y.;
- Cremer, Olaf;
- van der Poll, Tom;
- Schultz, Marcus J.
Publication type:
Article
The Search for Efficacious New Therapies in Sepsis Needs to Embrace Heterogeneity.
Published in:
2019
By:
- Scicluna, Brendon P;
- Baillie, J Kenneth
Publication type:
journal article
Understanding Heterogeneity in Biologic Phenotypes of Acute Respiratory Distress Syndrome by Leukocyte Expression Profiles.
Published in:
2019
By:
- Bos, Lieuwe Dj;
- Scicluna, Brendon P;
- Ong, David Y;
- Cremer, Olaf;
- van der Poll, Tom;
- Schultz, Marcus J;
- MARS consortium;
- Ong, David S Y;
- Cremer, Olaf L;
- Bos, Lieuwe D J
Publication type:
journal article
Molecular Biomarker to Assist in Diagnosing Abdominal Sepsis upon ICU Admission.
Published in:
2018
By:
- Scicluna, Brendon P.;
- Wiewel, Maryse A.;
- van Vught, Lonneke A.;
- Hoogendijk, Arie J.;
- Klarenbeek, Augustijn M.;
- Franitza, Marek;
- Toliat, Mohammad R.;
- Nürnberg, Peter;
- Horn, Janneke;
- Bonten, Marc J.;
- Schultz, Marcus J.;
- Cremer, Olaf L.;
- van der Poll, Tom
Publication type:
Letter
The Host Response in Patients with Sepsis Developing Intensive Care Unit-acquired Secondary Infections.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2017, v. 196, n. 4, p. 458, doi. 10.1164/rccm.201606-1225OC
By:
- van Vught, Lonneke A.;
- Wiewel, Maryse A.;
- Hoogendijk, Arie J.;
- Frencken, Jos F.;
- Scicluna, Brendon P.;
- Klein Klouwenberg, Peter M. C.;
- Zwinderman, Aeilko H.;
- Lutter, Rene;
- Horn, Janneke;
- Schultz, Marcus J.;
- Bonten, Marc M. J.;
- Cremer, Olaf L.;
- van der Poll, Tom
Publication type:
Article
Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients.
Published in:
2016
By:
- van Vught, Lonneke A.;
- Scicluna, Brendon P.;
- Wiewel, Maryse A.;
- Hoogendijk, Arie J.;
- Klouwenberg, Peter M. C. Klein;
- Franitza, Marek;
- Toliat, Mohammad R.;
- Nürnberg, Peter;
- Cremer, Olaf L.;
- Horn, Janneke;
- Schultz, Marcus J.;
- Bonten, Marc M. J.;
- van der Poll, Tom;
- Klein Klouwenberg, Peter M C
Publication type:
journal article
Reply: FAIM3:PLAC8 Ratio Compared with Existing Biomarkers for Diagnosis of Severe Community-acquired Pneumonia: Comparing Apples to Oranges?
Published in:
2016
By:
- Scicluna, Brendon P;
- van Vught, Lonneke A;
- van der Poll, Tom;
- Klein Klouwenberg, Peter M C;
- Cremer, Olaf L
Publication type:
commentary
Reply.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2016, v. 193, n. 1, p. 102, doi. 10.1164/rccm.201509-1752le
By:
- Scicluna, Brendon P.;
- van Vught, Lonneke A.;
- van der Poll, Tom;
- Klein Klouwenberg, Peter M. C.;
- Cremer, Olaf L.
Publication type:
Article
Reply: Comprehensive Validation of the FAIM3:PLAC8 Ratio in Time-matched Public Gene Expression Data.
Published in:
2015
By:
- Scicluna, Brendon P;
- Klein Klouwenberg, Peter M C;
- van der Poll, Tom;
- all the authors
Publication type:
commentary
Reply.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 192, n. 10, p. 1261, doi. 10.1164/rccm.201508-1552le
By:
- Scicluna, Brendon P.;
- Klein Klouwenberg, Peter M. C.;
- van der Poll, Tom
Publication type:
Article
A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission.
Published in:
2015
By:
- Scicluna, Brendon P.;
- Klein Klouwenberg, Peter M. C.;
- Van Vught, Lonneke A.;
- Wiewel, Maryse A.;
- Ong, David S. Y.;
- Zwinderman, Aeilko H.;
- Franitza, Marek;
- Toliat, Mohammad R.;
- Nürnberg, Peter;
- Hoogendijk, Arie J.;
- Horn, Janneke;
- Cremer, Olaf L.;
- Schultz, Marcus J.;
- Bonten, Marc J.;
- Van der Poll, Tom
Publication type:
journal article
Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection.
Published in:
PLoS Pathogens, 2021, v. 17, n. 4, p. 1, doi. 10.1371/journal.ppat.1009491
By:
- Qin, Wanhai;
- Brands, Xanthe;
- van 't Veer, Cornelis;
- F. de Vos, Alex;
- Sirard, Jean-Claude;
- J. T. H. Roelofs, Joris;
- P. Scicluna, Brendon;
- van der Poll, Tom
Publication type:
Article
The Primary Arrhythmia Syndromes: Same Mutation, Different Manifestations. Are We Starting to Understand Why?
Published in:
Journal of Cardiovascular Electrophysiology, 2008, v. 19, n. 4, p. 445, doi. 10.1111/j.1540-8167.2007.01073.x
By:
- SCICLUNA, BRENDON P.;
- WILDE, ARTHUR W.;
- BEZZINA, CONNIE R.
Publication type:
Article
Integrated single-cell analysis unveils diverging immune features of COVID-19, influenza, and other community-acquired pneumonia.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.69661
By:
- Schuurman, Alex R.;
- Reijnders, Tom D. Y.;
- Saris, Anno;
- Moral, Ivan Ramirez;
- Schinkel, Michiel;
- de Brabander, Justin;
- van Linge, Christine;
- Vermeulen, Louis;
- Scicluna, Brendon P.;
- Wiersinga, W. Joost;
- Braga, Felipe A. Vieira;
- van der Poll, Tom
Publication type:
Article
Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia.
Published in:
Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.00796
By:
- Brands, Xanthe;
- Haak, Bastiaan W.;
- Klarenbeek, Augustijn M.;
- Otto, Natasja A.;
- Faber, Daniël R.;
- Lutter, René;
- Scicluna, Brendon P.;
- Wiersinga, W. Joost;
- van der Poll, Tom
Publication type:
Article
Plasma fractalkine is a sustained marker of disease severity and outcome in sepsis patients.
Published in:
2015
By:
- Hoogendijk, Arie J.;
- Wiewel, Maryse A.;
- van Vught, Lonneke A.;
- Scicluna, Brendon P.;
- Belkasim-Bohoudi, Hakima;
- Horn, Janneke;
- Zwinderman, Aeilko H.;
- Klein Klouwenberg, Peter M. C.;
- Cremer, Olaf L.;
- Bonten, Marc J.;
- Schultz, Marcus J.;
- der Poll, Tom van;
- van der Poll, Tom;
- MARS consortium
Publication type:
journal article
Interleukin-27: a potential new sepsis biomarker exposed through genome-wide transcriptional profiling.
Published in:
Critical Care, 2012, v. 16, n. 6, p. 188, doi. 10.1186/cc11893
By:
- Scicluna, Brendon P.;
- van der Poll, Tom
Publication type:
Article
Interleukin-27: a potential new sepsis biomarker exposed through genome-wide transcriptional profiling.
Published in:
2012
By:
- Scicluna, Brendon P;
- van der Poll, Tom
Publication type:
journal article
Tubulin polymerization modifies cardiac sodium channel expression and gating.
Published in:
Cardiovascular Research, 2010, v. 85, n. 4, p. 691, doi. 10.1093/cvr/cvp352
By:
- Casini, Simona;
- Tan, Hanno L.;
- Demirayak, Ilker;
- Remme, Carol Ann;
- Amin, Ahmad S.;
- Scicluna, Brendon P.;
- Chatyan, Houssine;
- Ruijter, Jan M.;
- Bezzina, Connie R.;
- van Ginneken, Antoni C. G.;
- Veldkamp, Marieke W.
Publication type:
Article
Protease‐activated receptor 1 drives and maintains ductal cell fates in the premalignant pancreas and ductal adenocarcinoma.
Published in:
Molecular Oncology, 2021, v. 15, n. 11, p. 3091, doi. 10.1002/1878-0261.12971
By:
- Tekin, Cansu;
- Scicluna, Brendon P.;
- Lodestijn, Sophie C.;
- Shi, Kun;
- Bijlsma, Maarten F.;
- Spek, C. Arnold
Publication type:
Article
NLRP3 and ASC Differentially Affect the Lung Transcriptome during Pneumococcal Pneumonia.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2014, v. 50, n. 4, p. 699, doi. 10.1165/rcmb.2013-0015OC
By:
- van Lieshout, Miriam H.;
- Scicluna, Brendon P.;
- Florquin, Sandrine;
- van der Poll, Tom
Publication type:
Article
High-dimensional analysis reveals an immune atlas and novel neutrophil clusters in the lungs of model animals with Actinobacillus pleuropneumoniae-induced pneumonia.
Published in:
Veterinary Research, 2023, v. 54, n. 1, p. 1, doi. 10.1186/s13567-023-01207-4
By:
- Li, Na;
- Zhu, Junhui;
- Chen, Peiru;
- Bao, Chuntong;
- Wang, Jun;
- Abdelaal, Tamim;
- Chen, Dexi;
- Zhu, Sibo;
- Wang, Wenjing;
- Mao, Jiangnan;
- Scicluna, Brendon P.;
- Koning, Frits;
- Li, Fengyang;
- Lei, Liancheng
Publication type:
Article
Matrix metalloproteinase-8: a useful biomarker to refine the diagnosis of community-acquired pneumonia upon intensive care unit admission?
Published in:
2019
By:
- Uhel, Fabrice;
- Scicluna, Brendon P.;
- van Vught, Lonneke A.;
- Cremer, Olaf L.;
- Bonten, Marc J.;
- Schultz, Marcus J.;
- van der Poll, Tom
Publication type:
Letter
Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes.
Published in:
Intensive Care Medicine, 2023, v. 49, n. 11, p. 1360, doi. 10.1007/s00134-023-07239-w
By:
- van Amstel, Rombout B. E.;
- Kennedy, Jason N.;
- Scicluna, Brendon P.;
- Bos, Lieuwe D. J.;
- Peters-Sengers, Hessel;
- Butler, Joe M.;
- Cano-Gamez, Eddie;
- Knight, Julian C.;
- Vlaar, Alexander P. J.;
- Cremer, Olaf L.;
- Angus, Derek C.;
- van der Poll, Tom;
- Seymour, Christopher W.;
- van Vught, Lonneke A.;
- de Beer, Friso M.;
- Glas, Gerie J.;
- Hoogendijk, Arie J.;
- van Hooijdonk, Roosmarijn T. M.;
- Horn, Janneke;
- Huson, Mischa A.
Publication type:
Article
Source-specific host response and outcomes in critically ill patients with sepsis: a prospective cohort study.
Published in:
Intensive Care Medicine, 2022, v. 48, n. 1, p. 92, doi. 10.1007/s00134-021-06574-0
By:
- Peters-Sengers, Hessel;
- Butler, Joe M.;
- Uhel, Fabrice;
- Schultz, Marcus J.;
- Bonten, Marc J.;
- Cremer, Olaf L.;
- Scicluna, Brendon P.;
- van Vught, Lonneke A.;
- van der Poll, Tom;
- the MARS consortium;
- de Beer, Friso M.;
- Bos, Lieuwe D. J.;
- Glas, Gerie J.;
- van Hooijdonk, Roosmarijn T. M.;
- Horn, Janneke;
- Schouten, Laura R. A.;
- Straat, Marleen;
- Wieske, Luuk;
- Witteveen, Esther;
- Reijnders, Tom D. Y.
Publication type:
Article
Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study.
Published in:
Intensive Care Medicine, 2020, v. 46, n. 8, p. 1576, doi. 10.1007/s00134-020-06119-x
By:
- Uhel, Fabrice;
- Peters-Sengers, Hessel;
- Falahi, Fahimeh;
- Scicluna, Brendon P.;
- van Vught, Lonneke A.;
- Bonten, Marc J.;
- Cremer, Olaf L.;
- Schultz, Marcus J.;
- van der Poll, Tom
Publication type:
Article
Patients with hypothermic sepsis have a unique gene expression profile compared to patients with fever and sepsis.
Published in:
Journal of Cellular & Molecular Medicine, 2022, v. 26, n. 7, p. 1896, doi. 10.1111/jcmm.17156
By:
- Harmon, Matthew B. A.;
- Scicluna, Brendon P.;
- Wiewel, Maryse A.;
- Schultz, Marcus J.;
- Horn, Janneke;
- Cremer, Olaf L.;
- van der Poll, Tom;
- Joost Wiersinga, W.;
- Juffermans, Nicole P.;
- de Beer, Friso M;
- Bos, Lieuwe D;
- Glas, Gerie J;
- Hoogendijk, Arie J;
- van Hooijdonk, Roosmarijn T;
- Huson, Mischa A;
- Scicluna, Brendon;
- Schouten, Laura R;
- Schultz, Marcus J;
- Straat, Marleen;
- van Vught, Lonneke A.
Publication type:
Article
The circulatory small non‐coding RNA landscape in community‐acquired pneumonia on intensive care unit admission.
Published in:
Journal of Cellular & Molecular Medicine, 2021, v. 25, n. 16, p. 7621, doi. 10.1111/jcmm.16406
By:
- Khan, Hina N.;
- Jongejan, Aldo;
- van Vught, Lonneke A.;
- Horn, Janneke;
- Schultz, Marcus J.;
- Zwinderman, Aeilko H.;
- Cremer, Olaf L.;
- Bonten, Marc J.;
- van der Poll, Tom;
- Scicluna, Brendon P.
Publication type:
Article
Alveolar epithelial TET2 is not involved in the development of bleomycin‐induced pulmonary fibrosis.
Published in:
FASEB Journal, 2021, v. 35, n. 5, p. 1, doi. 10.1096/fj.202002686RR
By:
- Qin, Wanhai;
- Crestani, Bruno;
- Spek, C. Arnold;
- Scicluna, Brendon P.;
- van der Poll, Tom;
- Duitman, JanWillem
Publication type:
Article
Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseases.
Published in:
Science Immunology, 2021, v. 6, n. 55, p. 1, doi. 10.1126/sciimmunol.abd3489
By:
- van der Ploeg, Esmee K.;
- Golebski, Korneliusz;
- van Nimwegen, Menno;
- Fergusson, Joannah R.;
- Heesters, Balthasar A.;
- Martinez-Gonzalez, Itziar;
- Kradolfer, Chantal M. A.;
- van Tol, Sophie;
- Scicluna, Brendon P.;
- de Bruijn, Marjolein J. W.;
- de Boer, Geertje M.;
- Tramper-Stranders, Gerdien A.;
- Braunstahl, Gert-Jan;
- van IJcken, Wilfred F. J.;
- Nagtegaal, A. Paul;
- van Drunen, Cornelis M.;
- Fokkens, Wytske J.;
- Huylebroeck, Danny;
- Spits, Hergen;
- Hendriks, Rudi W.
Publication type:
Article
Combined Transcriptome and Proteome Leukocyte's Profiling Reveals Up-Regulated Module of Genes/Proteins Related to Low Density Neutrophils and Impaired Transcription and Translation Processes in Clinical Sepsis.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.744799
By:
- Leite, Giuseppe Gianini Figueirêdo;
- Ferreira, Bianca Lima;
- Tashima, Alexandre Keiji;
- Nishiduka, Erika Sayuri;
- Cunha-Neto, Edecio;
- Brunialti, Milena Karina Colo;
- Assuncao, Murillo;
- Azevedo, Luciano Cesar Pontes;
- Freitas, Flávio;
- van der Poll, Tom;
- Scicluna, Brendon P.;
- Salomão, Reinaldo
Publication type:
Article
The Role of Host Cell DNA Methylation in the Immune Response to Bacterial Infection.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.696280
By:
- Qin, Wanhai;
- Scicluna, Brendon P.;
- van der Poll, Tom
Publication type:
Article
Tenascin-C Deficiency Is Associated With Reduced Bacterial Outgrowth During Klebsiella pneumoniae -Evoked Pneumosepsis in Mice.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.600979
By:
- Meijer, Mariska T.;
- de Vos, Alex F.;
- Scicluna, Brendon P.;
- Roelofs, Joris J.;
- Abou Fayçal, Chérine;
- Orend, Gertraud;
- Uhel, Fabrice;
- van der Poll, Tom
Publication type:
Article
Corrigendum: Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia.
Published in:
2020
By:
- Brands, Xanthe;
- Haak, Bastiaan W.;
- Klarenbeek, Augustijn M.;
- Otto, Natasja A.;
- Faber, Daniël R.;
- Lutter, René;
- Scicluna, Brendon P.;
- Wiersinga, W. Joost;
- van der Poll, Tom
Publication type:
Correction Notice
Association between age and the host response in critically ill patients with sepsis.
Published in:
Critical Care, 2022, v. 26, n. 1, p. 1, doi. 10.1186/s13054-022-04266-9
By:
- Michels, Erik H. A.;
- Butler, Joe M.;
- Reijnders, Tom D. Y.;
- Cremer, Olaf L.;
- Scicluna, Brendon P.;
- Uhel, Fabrice;
- Peters-Sengers, Hessel;
- Schultz, Marcus J.;
- Knight, Julian C.;
- van Vught, Lonneke A.;
- van der Poll, Tom;
- MARS consortium;
- de Beer, Friso M.;
- Bos, Lieuwe D. J.;
- Glas, Gerie J.;
- Hoogendijk, Arie J.;
- van Hooijdonk, Roosmarijn T. M.;
- Horn, Janneke;
- Huson, Mischa A.;
- Schouten, Laura R. A.
Publication type:
Article
Effect of intravenous clarithromycin in patients with sepsis, respiratory and multiple organ dysfunction syndrome: a randomized clinical trial.
Published in:
Critical Care, 2022, v. 26, n. 1, p. 1, doi. 10.1186/s13054-022-04055-4
By:
- Karakike, Eleni;
- Scicluna, Brendon P.;
- Roumpoutsou, Maria;
- Mitrou, Ioannis;
- Karampela, Niki;
- Karageorgos, Athanasios;
- Psaroulis, Konstantinos;
- Massa, Eleni;
- Pitsoulis, Achillefs;
- Chaloulis, Panagiotis;
- Pappa, Evanthia;
- Schrijver, Irene T.;
- Frantzeskaki, Frantzeska;
- Lada, Malvina;
- Dauby, Nicolas;
- De Bels, David;
- Floros, Ioannis;
- Anisoglou, Souzana;
- Antoniadou, Eleni;
- Patrani, Maria
Publication type:
Article
Effect of intravenous clarithromycin in patients with sepsis, respiratory and multiple organ dysfunction syndrome: a randomized clinical trial.
Published in:
2022
By:
- Karakike, Eleni;
- Scicluna, Brendon P.;
- Roumpoutsou, Maria;
- Mitrou, Ioannis;
- Karampela, Niki;
- Karageorgos, Athanasios;
- Psaroulis, Konstantinos;
- Massa, Eleni;
- Pitsoulis, Achillefs;
- Chaloulis, Panagiotis;
- Pappa, Evanthia;
- Schrijver, Irene T.;
- Frantzeskaki, Frantzeska;
- Lada, Malvina;
- Dauby, Nicolas;
- De Bels, David;
- Floros, Ioannis;
- Anisoglou, Souzana;
- Antoniadou, Eleni;
- Patrani, Maria
Publication type:
journal article

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