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- Title
Gestasyonel Diyabette İnsülin Tedavi Gereksinimini Artıran Risk Faktörleri.
- Authors
BAYDUR ŞAHİN, Serap; AYAZ, Teslime; İLKKILIÇ, Kadir; SEZGİN, Hacer; METE URAL, Ülkü
- Abstract
Objective: Our aim was to determine the risk factors associated with the need for insulin therapy in patients with gestational diabetes mellitus (GDM). Material and Method: We enrolled 128 pregnant women who were diagnosed GDM by 75 gr oral glucose tolerance test (OGTT) at 24-28 week gestational weeks. The demographic features, insulin and HbAlc levels were evaluated. 35,2% of the patients needed insulin therapy during pregnancy. We compared patients with GDM who needed insulin therapy during pregnancy (insulin group) and women treated with diet alone (diet group). Results: The patients treated with insulin were older than the patients in diet group (32,0±0,6 vs, 34,7± 0,6; p=0.004), Prenatal body mass index (BMI) was significantly higher in the insulin group compared to the diet group (29±0,6 vs, 32± 0,8 kg/m²; p=0.004).While the mean fasting plasma glucose (FPG) levels was 101,6± 2,1 mg/dl in the insulin group, it was 92,7± 1,1 mg/dl in the diet group (p<0.001). While there was not a difference in OGTT 1 hour- plasma glucose levels between the two groups (p=0.069), 2 hour- plasma glucose levels were 159,1± 6,8 mg/dl in the insulin group and 143,1± 3,7 mg/dl in the diet group (p= 0.027). HbAlc level was significantly higher in the insulin group compared to the diet group (4,9± 0,1 vs, 5,3± 0,1; p= 0.001). There was not a difference in fasting insulin levels and HOMA-IR between the two groups (p=0.908, p=0.073). Conclusion: Age, family history of diabetes, prenatal BMI, FPG and HbAlc were found to be risk factors associated with insulin need in patients with GDM.
- Publication
Firat Tip Dergisi, 2014, Vol 19, Issue 4, p193
- ISSN
1300-9818
- Publication type
Article