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- Title
A New Isochroman Derivative from the Marine Fungus Phomopsis sp. (No. Gx-4).
- Authors
Yang, Jian; Qiu, ShengXiang; She, Zhigang; Lin, Yongcheng
- Abstract
A new isochroman, (3R,4S)-3,4-dihydro-8-hydroxy-4-methoxy-3-methylisocoumarin ( 1), and three known compounds were isolated from the marine fungus Phomopsis sp. (No. Gx-4). Their structures were determined by spectroscopic methods, mainly 1D and 2D NMR. Primary bioassays and preliminary pharmacological tests revealed that compounds 1 and 3 can accelerate the growth of subintestinal vessel plexus (SIV) branches markedly, but compounds 2 and 4 can inhibit their growth.
- Subjects
PHOMOPSIS; PHOMOPSIS diseases; SPHAEROPSIDACEAE; BIOLOGICAL assay; PHARMACOLOGY
- Publication
Chemistry of Natural Compounds, 2014, Vol 50, Issue 3, p424
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-014-0976-y